RT Journal Article T1 Primary cardiac fibroma in infants: A case report and review of cases of cardiac fibroma managed through orthotopic heart transplant A1 Rodriguez-Gonzalez, Moises A1 Pérez-Reviriego, Alvaro A. A1 Gómez-Guzmán, Elena A1 Tejero-Hernández, María Ángeles A1 Zorilla Sanz, Alicia A1 Valverde, Israel K1 Cardiac fibroma K1 Orthotopic heart transplant K1 Infants K1 Mortality K1 Primary cardiac tumor K1 Trasplantes K1 Trasplante de corazón K1 Neoplasias cardíacas K1 Procedimientos quirúrgicos cardíacos K1 Lactante K1 Niño K1 Mortalidad AB Cardiac fibromas (CF) are the second most common cardiac tumors in children. They can be aggressive tumors despite their benign histopathologic nature, accounting for the highest mortality rate among primary cardiac tumors. CF usually show a progressive growth and spontaneous regression is rare. Therefore, a complete surgical excision is the preferred therapeutic approach when patients become symptomatic or if mass-related life-threatening complications are anticipated, even in asymptomatic patients. However, some cases are not good candidates for surgical excision due to the impossibility of preserving a normal cardiac anatomy or function after the tumor resection. Orthotopic heart transplantation (OHT) can be an exceptional but adequate alternative for some giant unresectable CF in children. In this article, we report our experience with the case of a 7-month-old infant with a giant unresectable cardiac fibroma who was successfully managed through OHT. PB Wolters Kluwer ‑ Medknow SN 0974-2069 YR 2021 FD 2021-04-10 LK http://hdl.handle.net/10668/4522 UL http://hdl.handle.net/10668/4522 LA en NO Rodriguez-Gonzalez M, Pérez-Reviriego AA, Gómez-Guzmán E, Tejero-Hernández MÁ, Sanz AZ, Valverde I. Primary cardiac fibroma in infants: A case report and review of cases of cardiac fibroma managed through orthotopic heart transplant. Ann Pediatr Cardiol. 2021 Apr-Jun;14(2):224-227 DS RISalud RD Apr 7, 2025