TY - JOUR AU - Cazet, Aurélie S AU - Hui, Mun N AU - Elsworth, Benjamin L AU - Wu, Sunny Z AU - Roden, Daniel AU - Chan, Chia-Ling AU - Skhinas, Joanna N AU - Collot, Raphaël AU - Yang, Jessica AU - Harvey, Kate AU - Johan, M Zahied AU - Cooper, Caroline AU - Nair, Radhika AU - Herrmann, David AU - McFarland, Andrea AU - Deng, Niantao AU - Ruiz-Borrego, Manuel AU - Rojo, Federico AU - Trigo, José M AU - Bezares, Susana AU - Caballero, Rosalía AU - Lim, Elgene AU - Timpson, Paul AU - O'Toole, Sandra AU - Watkins, D Neil AU - Cox, Thomas R AU - Samuel, Michael S AU - Martín, Miguel AU - Swarbrick, Alexander PY - 2018 DO - 10.1038/s41467-018-05220-6 UR - http://hdl.handle.net/10668/12750 T2 - Nature communications AB - The cellular and molecular basis of stromal cell recruitment, activation and crosstalk in carcinomas is poorly understood, limiting the development of targeted anti-stromal therapies. In mouse models of triple negative breast cancer (TNBC), Hedgehog... LA - en KW - Adult KW - Aged KW - Anilides KW - Animals KW - Antineoplastic Combined Chemotherapy Protocols KW - Biphenyl Compounds KW - Cell Line, Tumor KW - Docetaxel KW - Drug Resistance, Neoplasm KW - Female KW - Humans KW - Mice, Inbred NOD KW - Mice, Knockout KW - Mice, SCID KW - Middle Aged KW - Neoplastic Stem Cells KW - Pyridines KW - Treatment Outcome KW - Triple Negative Breast Neoplasms KW - Xenograft Model Antitumor Assays TI - Targeting stromal remodeling and cancer stem cell plasticity overcomes chemoresistance in triple negative breast cancer. TY - research article VL - 9 ER -