TY  - JOUR
AU  - Nicoletti, Paola
AU  - Carr, Daniel F
AU  - Barrett, Sarah
AU  - McEvoy, Laurence
AU  - Friedmann, Peter S
AU  - Shear, Neil H
AU  - Nelson, Matthew R
AU  - Chiriac, Anca M
AU  - Blanca-Lopez, Natalia
AU  - Cornejo-Garcia, Jose A
AU  - Gaeta, Francesco
AU  - Nakonechna, Alla
AU  - Torres, Maria J
AU  - Caruso, Cristiano
AU  - Valluzzi, Rocco L
AU  - Floratos, Aris
AU  - Shen, Yufeng
AU  - Pavlos, Rebecca K
AU  - Phillips, Elizabeth J
AU  - Demoly, Pascal
AU  - Romano, Antonino
AU  - Blanca, Miguel
AU  - Pirmohamed, Munir
PY  - 2020
DO  - 10.1016/j.jaci.2020.10.004
UR  - http://hdl.handle.net/10668/16426
T2  - The Journal of allergy and clinical immunology
AB  - β-lactam antibiotics are associated with a variety of immune-mediated or hypersensitivity reactions, including immediate (type I) reactions mediated by antigen-specific IgE. We sought to identify genetic predisposing factors for immediate reactions to...
LA  - en
PB  - Elsevier
KW  - Type I hypersensitivity
KW  - Allergy
KW  - Anaphylaxis
KW  - Cephalosporins
KW  - Penicillins
KW  - Pharmacogenomics
KW  - β-lactams
KW  - Adult
KW  - Anti-Bacterial Agents
KW  - Cephalosporins
KW  - Cohort Studies
KW  - Drug Hypersensitivity
KW  - Female
KW  - Genetic Predisposition to Disease
KW  - Genome-Wide Association Study
KW  - HLA-DQ alpha-Chains
KW  - HLA-DRB1 Chains
KW  - Humans
KW  - Hypersensitivity, Immediate
KW  - Male
KW  - Middle Aged
KW  - Penicillins
KW  - Phenotype
KW  - Polymorphism, Single Nucleotide
TI  - Beta-lactam-induced immediate hypersensitivity reactions: A genome-wide association study of a deeply phenotyped cohort.
TY  - research article
VL  - 147
ER  -