TY - JOUR AU - Quesada, Andrés AU - Segarra, Ana Belén AU - Montoro-Molina, Sebastián AU - de Gracia, María Del Carmen AU - Osuna, Antonio AU - O'Valle, Francisco AU - Gómez-Guzmán, Manuel AU - Vargas, Félix AU - Wangensteen, Rosemary PY - 2017 DO - 10.1371/journal.pone.0175462 UR - http://hdl.handle.net/10668/2689 T2 - PloS One AB - PURPOSE:The aim of this work was to investigate if the content of glutamyl aminopeptidase (GluAp) in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats.METHODS:Urine samples were collected 24... LA - en PB - Public Library of Science KW - Animales KW - Antígenos CD13 KW - Peso corporal KW - Centrifugación KW - Cisplatino KW - Creatinina KW - Técnicas para inmunoenzimas KW - Espacio extracelular KW - Glutamil aminopeptidasa KW - Pruebas de función renal KW - Neoplasias KW - Ratas KW - Aumento de peso KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Exopeptidases::Aminopeptidases::Antigens, CD13 KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Body Constitution::Body Weights and Measures::Body Size::Body Weight KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Centrifugation KW - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Chlorine Compounds::Cisplatin KW - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Creatinine KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunoassay::Immunoenzyme Techniques KW - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Extracellular Space KW - Medical Subject Headings::Chemicals and Drugs::Enzymes and Coenzymes::Enzymes::Hydrolases::Peptide Hydrolases::Exopeptidases::Aminopeptidases::Glutamyl Aminopeptidase KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunoassay::Immunoblotting KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Urological::Kidney Function Tests KW - Medical Subject Headings::Diseases::Neoplasms KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Rats KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Physiological Processes::Growth and Development::Growth::Body Size::Body Weight::Body Weight Changes::Weight Gain TI - Glutamyl aminopeptidase in microvesicular and exosomal fractions of urine is related with renal dysfunction in cisplatin-treated rats TY - research article ER -