TY - JOUR AU - Lacroix, Matthieu AU - Linares, Laetitia K AU - Rueda-Rincon, Natalia AU - Bloch, Katarzyna AU - Di Michele, Michela AU - De Blasio, Carlo AU - Fau, Caroline AU - Gayte, Laurie AU - Blanchet, Emilie AU - Mairal, Aline AU - Derua, Rita AU - Cardona, Fernando AU - Beuzelin, Diane AU - Annicotte, Jean-Sebastien AU - Pirot, Nelly AU - Torro, Adeline AU - Tinahones, Francisco J AU - Bernex, Florence AU - Bertrand-Michel, Justine AU - Langin, Dominique AU - Fajas, Lluis AU - Swinnen, Johannes V AU - Le Cam, Laurent PY - 2021 DO - 10.1038/s41467-021-27307-3 UR - https://hdl.handle.net/10668/26950 T2 - Nature communications AB - Growing evidence supports the importance of the p53 tumor suppressor in metabolism but the mechanisms underlying p53-mediated control of metabolism remain poorly understood. Here, we identify the multifunctional E4F1 protein as a key regulator of p53... LA - en KW - Adipocytes KW - Adipose Tissue KW - Adult KW - Aged KW - Animals KW - Body Mass Index KW - Fatty Acids, Monounsaturated KW - Female KW - Gene Expression Regulation KW - Humans KW - Insulin Resistance KW - Lipid Metabolism KW - Male KW - Mice KW - Mice, Knockout KW - Middle Aged KW - Obesity KW - Repressor Proteins KW - Signal Transduction KW - Stearoyl-CoA Desaturase KW - Tumor Suppressor Protein p53 KW - Ubiquitin-Protein Ligases TI - The multifunctional protein E4F1 links P53 to lipid metabolism in adipocytes. TY - research article VL - 12 ER -