TY - GEN AU - Rodríguez-Rubio, Miguel AU - Figueira, Juan Carlos AU - Acuña-Castroviejo, Darío AU - Borobia, Alberto M. AU - Escames, Germaine AU - de la Oliva, Pedro PY - 2020 DO - 10.1186/s13063-020-04632-4 UR - http://hdl.handle.net/10668/3393 T2 - Trials LA - en PB - BioMed Central KW - COVID-19 KW - Randomized controlled trial KW - Protocol KW - Melatonin KW - Treatment KW - Intensive care KW - ARDS KW - Inflammation KW - Infecciones por coronavirus KW - Ensayo clínico controlado aleatorio KW - Protocolo de ensayo clínico KW - Melatonina KW - Terapéutica KW - Unidades de cuidados intensivos KW - Síndrome de dificultad respiratoria del adulto KW - Inflamación KW - Medical Subject Headings::Diseases::Respiratory Tract Diseases::Respiration Disorders::Respiratory Distress Syndrome, Adult KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Drug Therapy::Drug Administration Routes::Administration, Intravenous KW - Medical Subject Headings::Diseases::Virus Diseases::RNA Virus Infections::Nidovirales Infections::Coronaviridae Infections::Coronavirus Infections KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Double-Blind Method KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Health Care::Health Care Facilities, Manpower, and Services::Health Facilities::Hospital Units::Intensive Care Units KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Patient Care::Hospitalization::Length of Stay KW - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Melatonin KW - Medical Subject Headings::Health Care::Environment and Public Health::Public Health::Disease Outbreaks::Epidemics::Pandemics KW - Medical Subject Headings::Diseases::Virus Diseases::Pneumonia, Viral KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Clinical Trials as Topic::Controlled Clinical Trials as... TI - A phase II, single-center, double-blind, randomized placebo-controlled trial to explore the efficacy and safety of intravenous melatonin in patients with COVID-19 admitted to the intensive care unit (MelCOVID study): a structured summary of a study protocol for a randomized controlled trial TY - letter ER -