TY  - JOUR
AU  - Pertusa, José A G
AU  - León-Quinto, Trinidad
AU  - Berná, Genoveva
AU  - Tejedo, Juan R
AU  - Hmadcha, Abdelkrim
AU  - Bedoya, Francisco J
AU  - Martín, Franz
AU  - Soria, Bernat
PY  - 2017
DO  - 10.1371/journal.pone.0187547
UR  - http://hdl.handle.net/10668/11765
T2  - PloS one
AB  - β-cells release hexameric Zn2+-insulin into the extracellular space, but monomeric Zn2+-free insulin appears to be the only biologically active form. The mechanisms implicated in dissociation of the hexamer remain unclear, but they seem to be Zn2+...
LA  - en
KW  - Animals
KW  - Blood Glucose
KW  - Chelating Agents
KW  - Exocytosis
KW  - Insulin
KW  - Islets of Langerhans
KW  - Male
KW  - Mice
KW  - Radioimmunoassay
KW  - Rats
KW  - Rats, Wistar
KW  - Serum Albumin
KW  - Zinc
TI  - Zn2+ chelation by serum albumin improves hexameric Zn2+-insulin dissociation into monomers after exocytosis.
TY  - research article
VL  - 12
ER  -