RT Journal Article
T1 Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19.
A1 Di Mascio, Daniele
A1 Sen, Cihat
A1 Saccone, Gabriele
A1 Galindo, Alberto
A1 Grünebaum, Amos
A1 Yoshimatsu, Jun
A1 Stanojevic, Milan
A1 Kurjak, Asım
A1 Chervenak, Frank
A1 Rodríguez Suárez, María José
A1 Gambacorti-Passerini, Zita Maria
A1 Baz, María de Los Angeles Anaya
A1 Aguilar Galán, Esther Vanessa
A1 López, Yolanda Cuñarro
A1 De León Luis, Juan Antonio
A1 Hernández, Ignacio Cueto
A1 Herraiz, Ignacio
A1 Villalain, Cecilia
A1 Venturella, Roberta
A1 Rizzo, Giuseppe
A1 Mappa, Ilenia
A1 Gerosolima, Giovanni
A1 Hellmeyer, Lars
A1 Königbauer, Josefine
A1 Ameli, Giada
A1 Frusca, Tiziana
A1 Volpe, Nicola
A1 Luca Schera, Giovanni Battista
A1 Fieni, Stefania
A1 Esposito, Eutalia
A1 Simonazzi, Giuliana
A1 Di Donna, Gaetana
A1 Youssef, Aly
A1 Della Gatta, Anna Nunzia
A1 Di Donna, Mariano Catello
A1 Chiantera, Vito
A1 Buono, Natalina
A1 Sozzi, Giulio
A1 Greco, Pantaleo
A1 Morano, Danila
A1 Bianchi, Beatrice
A1 Lombana Marino, Maria Giulia
A1 Laraud, Federica
A1 Ramone, Arianna
A1 Cagnacci, Angelo
A1 Barra, Fabio
A1 Gustavino, Claudio
A1 Ferrero, Simone
A1 Ghezzi, Fabio
A1 Cromi, Antonella
A1 Laganà, Antonio Simone
A1 Laurita Longo, Valentina
A1 Stollagli, Francesca
A1 Sirico, Angelo
A1 Lanzone, Antonio
A1 Driul, Lorenza
A1 Cecchini D, Fabiana
A1 Xodo, Serena
A1 Rodriguez, Brian
A1 Mercado-Olivares, Felipe
A1 Elkafrawi, Deena
A1 Sisti, Giovanni
A1 Esposito, Rosanna
A1 Coviello, Antonio
A1 Cerbone, Marco
A1 Morlando, Maddalena
A1 Schiattarella, Antonio
A1 Colacurci, Nicola
A1 De Franciscis, Pasquale
A1 Cataneo, Ilaria
A1 Lenzi, Marinella
A1 Sandri, Fabrizio
A1 Buscemi, Riccardo
A1 Gattei, Giorgia
A1 Sala, Francesca Della
A1 Valori, Eleonora
A1 Rovellotti, Maria Cristina
A1 Done, Elisa
A1 Faron, Gilles
A1 Gucciardo, Leonardo
A1 Esposito, Valentina
A1 Vena, Flaminia
A1 Giancotti, Antonella
A1 Brunelli, Roberto
A1 Muzii, Ludovico
A1 Nappi, Luigi
A1 Sorrentino, Felice
A1 Vasciaveo, Lorenzo
A1 Liberati, Marco
A1 Buca, Danilo
A1 Leombroni, Martina
A1 Di Sebastiano, Francesca
A1 Di Tizio, Luciano
A1 Gazzolo, Diego
A1 Franchi, Massimo
A1 Ianniciello, Quintino Cesare
A1 Garzon, Simone
A1 Petriglia, Giuliano
A1 Borrello, Leonardo
A1 Nieto-Calvache, Albaro Josè
A1 Burgos-Luna, Juan Manuel
A1 Kadji, Caroline
A1 Carlin, Andrew
A1 Bevilacqua, Elisa
A1 Moucho, Marina
A1 Pinto, Pedro Viana
A1 Figueiredo, Rita
A1 Morales Roselló, José
A1 Loscalzo, Gabriela
A1 Martinez-Varea, Alicia
A1 Diago, Vincente
A1 Jimenez Lopez, Jesús S
A1 Aykanat, Alicia Yeliz
A1 Cosma, Stefano
A1 Carosso, Andrea
A1 Benedetto, Chiara
A1 Bermejo, Amanda
A1 May Feuerschuette, Otto Henrique
A1 Uyaniklar, Ozlem
A1 Ocakouglu, Sakine Rahimli
A1 Atak, Zeliha
A1 Gündüz, Reyhan
A1 Haberal, Esra Tustas
A1 Froessler, Bernd
A1 Parange, Anupam
A1 Palm, Peter
A1 Samardjiski, Igor
A1 Taccaliti, Chiara
A1 Okuyan, Erhan
A1 Daskalakis, George
A1 Moreira de Sa, Renato Augusto
A1 Pittaro, Alejandro
A1 Gonzalez-Duran, Maria Luisa
A1 Guisan, Ana Concheiro
A1 Genç, Şerife Özlem
A1 Zlatohlávková, Blanka
A1 Piqueras, Anna Luengo
A1 Oliva, Dolores Esteban
A1 Cil, Aylin Pelin
A1 Api, Olus
A1 Antsaklis, Panos
A1 Ples, Liana
A1 Kyvernitakis, Ioannis
A1 Maul, Holger
A1 Malan, Marcel
A1 Lila, Albert
A1 Granese, Roberta
A1 Ercoli, Alfredo
A1 Zoccali, Giuseppe
A1 Villasco, Andrea
A1 Biglia, Nicoletta
A1 Madalina, Ciuhodaru
A1 Costa, Elena
A1 Daelemans, Caroline
A1 Pintiaux, Axelle
A1 Cueto, Elisa
A1 Hadar, Eran
A1 Dollinger, Sarah
A1 Brzezinski Sinai, Noa A
A1 Huertas, Erasmo
A1 Arango, Pedro
A1 Sanchez, Amadeo
A1 Schvartzman, Javier Alfonso
A1 Cojocaru, Liviu
A1 Turan, Sifa
A1 Turan, Ozhan
A1 Di Dedda, Maria Carmela
A1 Molpeceres, Rebeca Garrote
A1 Zdjelar, Snezana
A1 Premru-Srsen, Tanja
A1 Cerar, Lilijana Kornhauser
A1 Druškovič, Mirjam
A1 De Robertis, Valentina
A1 Stefanovic, Vedran
A1 Nupponen, Irmeli
A1 Nelskylä, Kaisa
A1 Khodjaeva, Zulfiya
A1 Gorina, Ksenia A
A1 Sukhikh, Gennady T
A1 Maruotti, Giuseppe Maria
A1 Visentin, Silvia
A1 Cosmi, Erich
A1 Ferrari, Jacopo
A1 Gatti, Alessandra
A1 Luvero, Daniela
A1 Angioli, Roberto
A1 Puri, Ludovica
A1 Palumbo, Marco
A1 D'Urso, Giusella
A1 Colaleo, Francesco
A1 Chiara Rapisarda, Agnese Maria
A1 Carbone, Ilma Floriana
A1 Mollo, Antonio
A1 Nazzaro, Giovanni
A1 Locci, Mariavittoria
A1 Guida, Maurizio
A1 Di Spiezio Sardo, Attilio
A1 Panici, Pierluigi Benedetti
A1 Berghella, Vincenzo
A1 Flacco, Maria Elena
A1 Manzoli, Lamberto
A1 Bifulco, Giuseppe
A1 Scambia, Giovanni
A1 Zullo, Fulvio
A1 D'Antonio, Francesco
K1 Coronavirus
K1 perinatal morbidity
K1 perinatal mortality
AB Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pregnancy loss before 22 weeks of gestations), stillbirth (intrauterine fetal death after 22 weeks of gestation), neonatal death (death of a live-born infant within the first 28 days of life), and perinatal death (either stillbirth or neonatal death). Logistic regression analysis was performed to evaluate parameters independently associated with the primary outcome. Logistic regression was reported as odds ratio (OR) with 95% confidence interval (CI). Results Mean gestational age at diagnosis was 30.6±9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. There were six miscarriage (2.3%), six intrauterine device (IUD) (2.3) and 5 (2.0%) neonatal deaths, with an overall rate of perinatal death of 4.2% (11/265), thus resulting into 17 cases experiencing and 226 not experiencing composite adverse fetal outcome. Neither stillbirths nor neonatal deaths had congenital anomalies found at antenatal or postnatal evaluation. Furthermore, none of the cases experiencing IUD had signs of impending demise at arterial or venous Doppler. Neonatal deaths were all considered as prematurity-related adverse events. Of the 250 live-born neonates, one (0.4%) was found positive at RT-PCR pharyngeal swabs performed after delivery. The mother was tested positive during the third trimester of pregnancy. The newborn was asymptomatic and had negative RT-PCR test after 14 days of life. At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; p
YR 2020
FD 2020
LK https://hdl.handle.net/10668/24421
UL https://hdl.handle.net/10668/24421
LA en
DS RISalud
RD Apr 7, 2025