TY - JOUR AU - Lucena, María Isabel AU - García-Martín, Elena AU - Daly, Ann K AU - Blanca, Miguel AU - Andrade, Raúl J AU - Agúndez, José A G PY - 2019 DO - 10.3389/fgene.2019.00134 SN - 1664-8021 UR - http://hdl.handle.net/10668/13713 T2 - Frontiers in genetics AB - Purpose: The etiopathogenesis of drug-induced liver injury (DILI) is still far from being elucidated. This study aims to the study of genetic variations in DILI, related to the drug target, and specifically in the genes coding for the cyclooxygenase... LA - en KW - COX1 KW - COX2 KW - PTGS1 KW - PTGS2 KW - drug-induced liver injury KW - next generation sequencing TI - Next-Generation Sequencing of PTGS Genes Reveals an Increased Frequency of Non-synonymous Variants Among Patients With NSAID-Induced Liver Injury. TY - research article VL - 10 ER -