RT Journal Article
T1 Relationship between Night Shifts and Risk of Breast Cancer among Nurses: A Systematic Review.
A1 Fagundo-Rivera, Javier
A1 Gómez-Salgado, Juan
A1 García-Iglesias, Juan Jesús
A1 Gómez-Salgado, Carlos
A1 Camacho-Martín, Selena
A1 Ruiz-Frutos, Carlos
K1 breast cancer
K1 circadian rhythm
K1 environmental
K1 night shift work
K1 nurses
K1 occupational exposure
K1 shift work schedule
AB The incidence of breast cancer worldwide has increased in recent decades, accounting for 1 in 3 neoplasms in women. Besides, nurses are mainly represented by the female collective, most of them, undertaking working conditions with intensive rotative and night shifts due to the 24-h pace of work of this profession. The objective of this study was to assess the possible relationship between shift work, especially night-time work, and the development of breast cancer among nurses. A systematic review of the literature was carried out through the consultation of the following databases: Cochrane Plus Library, PubMed, CINAHL (Cumulative Index to Nursing and Allied Health Literature), Web of Science, ScienceDirect, Scopus, and Dialnet. Records were selected between 2010 and 2020, in Spanish and English, which covered the association between breast cancer diagnosed among nursing professionals and rotating night shifts. A total of 12 studies were identified after critical reading. Most of the studies found an association between breast cancer and consecutive rotating night shifts prolonged over time. Among the associated factors, the alteration of the circadian rhythm influenced the expression of peripheral clock genes, which was the same as reproductive hormones. The risk of breast cancer in nurses increased during early adulthood and after 5 or more years with 6 or more consecutive nights. The different studies of this review show significant associations between breast cancer and prolonged rotating night shifts. Similarly, there is a relationship between the alterations in certain circadian rhythm markers (such as melatonin), epigenetic markers (such as telomeres), and breast cancer that would require more studies in order to corroborate these findings.
YR 2020
FD 2020-12-10
LK http://hdl.handle.net/10668/16796
UL http://hdl.handle.net/10668/16796
LA en
DS RISalud
RD Apr 6, 2025