RT Journal Article
T1 Amniotic fluid iodine concentrations do not vary in pregnant women with varying iodine intake.
A1 García-Fuentes, Eduardo
A1 Gallo, Manuel
A1 García, Laureano
A1 Prieto, Stephanie
A1 Alcaide-Torres, Javier
A1 Santiago, Piedad
A1 Velasco, Inés
A1 Soriguer, Federico
K1 Iodine
K1 Amniotic fluid
K1 Pregnancy
K1 Líquido amniótico
K1 Yodo
K1 Embarazo
K1 Suplementos Dietéticos
K1 Estado Nutricional
K1 Yoduro potásico
K1 Cloruro sódico dietético
AB Iodine deficiency is an important clinical and public health problem. Its prevention begins with an adequate intake of iodine during pregnancy. International agencies recommend at least 200 microg iodine per d for pregnant women. We assessed whether iodine concentrations in the amniotic fluid of healthy pregnant women are independent of iodine intake. This cross-sectional, non-interventional study included 365 consecutive women who underwent amniocentesis to determine the fetal karyotype. The amniocentesis was performed with abdominal antisepsis using chlorhexidine. The iodine concentration was measured in urine and amniotic fluid. The study variables were the intake of iodized salt and multivitamin supplements or the prescription of a KI supplement. The mean level of urinary iodine was 139.0 (SD 94.5) microg/l and of amniotic fluid 15.81 (SD 7.09) microg/l. The women who consumed iodized salt and those who took a KI supplement had significantly higher levels of urinary iodine than those who did not (P = 0.01 and P = 0.004, respectively). The urinary iodine levels were not significantly different in the women who took a multivitamin supplement compared with those who did not take this supplement, independently of iodine concentration or multivitamin supplement. The concentrations of iodine in the amniotic fluid were similar, independent of the dietary iodine intake. Urine and amniotic fluid iodine concentrations were weakly correlated, although the amniotic fluid values were no higher in those women taking a KI supplement. KI prescription at recommended doses increases the iodine levels in the mother without influencing the iodine levels in the amniotic fluid.
PB Nutrition Society
SN 0007-1145
YR 2008
FD 2008-06
LK http://hdl.handle.net/10668/1305
UL http://hdl.handle.net/10668/1305
LA en
NO García-Fuentes E, Gallo M, García L, Prieto S, Alcaide-Torres J, Santiago P, et al. Amniotic fluid iodine concentrations do not vary in pregnant women with varying iodine intake. Br. J. Nutr.. 2008; 99(6):1178-81
NO Comparative Study; Journal Article; Research Support, Non-U.S. Gov't;
DS RISalud
RD Apr 5, 2025