RT Journal Article
T1 FLAIR-hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES) in a patient with Crohn's disease on anti-TNF treatment.
T2 Lesiones hiperintensas en FLAIR asociadas a encefalitis con convulsiones por anticuerpos anti-MOG en un paciente con enfermedad de Crohn en tratamiento con fármacos anti-TNF.
A1 Cabezudo-Garcia, P
A1 Vidal-Denis, M
A1 Ciano-Petersen, N L
A1 Irigoyen-Oyarzabal, M V
A1 Serrano-Castro, P J
K1 Fever
K1 Headache
K1 Antibodies
K1 Encephalitis
AB The FLAIR-hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES) were first described by Ogawa et al. in 2017 as a distinctive clinical-radiological syndrome from other anti-MOG antibody-associated demyelination syndromes, often with a more indolent course. The most frequent clinical manifestations of this syndrome are seizures, headache, fever, and focal cortical deficits congruent with the localization of unilateral cortical FLAIR hyperintense lesions, although bi-hemispheric involvement is not uncommon. The etiology and risk factors for developing the syndrome remain unknown. Some cases have been associated with concomitant anti-NMDAR antibodies, but the association of anti-MOG-related disorders with other autoimmune diseases seems rare. Recently, a case of FLAMES in a patient with inflammatory bowel disease (ulcerative colitis) on TNF inhibitor therapy has been reported.
PB Elsevier
YR 2021
FD 2021
LK http://hdl.handle.net/10668/22448
UL http://hdl.handle.net/10668/22448
LA en
LA es
NO Cabezudo-García P, Vidal Denis M, Ciano-Petersen NL, Irigoyen-Oyarzábal MV, Serrano-Castro PJ. FLAIR-hyperintense lesions in anti-MOG-associated encephalitis with seizures (FLAMES) in a patient with Crohn's disease on anti-TNF treatment. Neurologia (Engl Ed). 2022 May;37(4):304-306. English, Spanish
DS RISalud
RD Apr 7, 2025