RT Journal Article T1 Accuracy of competing-risks model in screening for pre-eclampsia by maternal factors and biomarkers at 11-13 weeks' gestation. A1 O'Gorman, N A1 Wright, D A1 Poon, L C A1 Rolnik, D L A1 Syngelaki, A A1 Wright, A A1 Akolekar, R A1 Cicero, S A1 Janga, D A1 Jani, J A1 Molina, F S A1 de Paco Matallana, C A1 Papantoniou, N A1 Persico, N A1 Plasencia, W A1 Singh, M A1 Nicolaides, K H K1 Bayes' theorem K1 first-trimester screening K1 mean arterial pressure K1 placental growth factor K1 pre-eclampsia K1 pregnancy-associated plasma protein-A K1 pyramid of pregnancy care K1 survival model K1 uterine artery Doppler AB To examine the diagnostic accuracy of a previously developed model for prediction of pre-eclampsia (PE) by a combination of maternal factors and biomarkers at 11-13 weeks' gestation. This was a prospective first-trimester multicenter study of screening for PE in 8775 singleton pregnancies. A previously published algorithm was used for the calculation of patient-specific risk of PE in each individual. The detection rates (DRs) and false-positive rates (FPRs) for delivery with PE In the study population, 239 (2.7%) cases developed PE, of which 17 (0.2%), 59 (0.7%) and 180 (2.1%) developed PE Assessment of a combination of maternal factors and biomarkers at 11-13 weeks provides effective first-trimester screening for preterm PE. Copyright © 2017 ISUOG. Published by John Wiley & Sons Ltd. YR 2017 FD 2017-05-14 LK http://hdl.handle.net/10668/10757 UL http://hdl.handle.net/10668/10757 LA en DS RISalud RD Apr 14, 2025