TY - JOUR AU - Lorente, David AU - Olmos, David AU - Mateo, Joaquin AU - Bianchini, Diletta AU - Seed, George AU - Fleisher, Martin AU - Danila, Daniel C. AU - Flohr, Penny AU - Crespo, Mateus AU - Figueiredo, Ines AU - Miranda, Susana AU - Baeten, Kurt AU - Molina, Arturo AU - Kheoh, Thian AU - McCormack, Robert AU - Terstappen, Leon W. M. M. AU - Scher, Howard I. AU - de-Bono, Johann S. PY - 2017 DO - 10.1016/j.eururo.2016.05.023 SN - 0302-2838 UR - http://hdl.handle.net/10668/18775 T2 - European urology AB - Background: Treatment response biomarkers are urgently needed for castration-resistant prostate cancer (CRPC). Baseline and post-treatment circulating tumor cell (CTC) counts of >= 5 cells/7.5 ml are associated with poor CRPC outcome.Objective: To... LA - en PB - Elsevier science bv KW - Castration-resistant prostate cancer KW - Treatment outcome KW - Response KW - Circulating tumor cells KW - Abiraterone KW - Chemotherapy KW - Abiraterone acetate KW - Increased survival KW - End-points KW - Chemotherapy KW - Enzalutamide KW - Antigen KW - Trial KW - Surrogacy KW - Docetaxel KW - Biomarker KW - Androstenes KW - Antineoplastic Combined Chemotherapy Protocols KW - Cell Count KW - Clinical Trials as Topic KW - Humans KW - Kaplan-Meier Estimate KW - Logistic Models KW - Male KW - Multivariate Analysis KW - Neoplasm Metastasis KW - Neoplastic Cells, Circulating KW - Prednisone KW - Proportional Hazards Models KW - Prostatic Neoplasms, Castration-Resistant TI - Decline in Circulating Tumor Cell Count and Treatment Outcome in Advanced Prostate Cancer TY - research article VL - 70 ER -