RT Journal Article
T1 The Gut Microbiota and Its Implication in the Development of Atherosclerosis and Related Cardiovascular Diseases
A1 Sanchez-Rodriguez, Estefania
A1 Egea-Zorrilla, Alejandro
A1 Plaza-Díaz, Julio
A1 Aragón-Vela, Jerónimo
A1 Muñoz-Quezada, Sergio
A1 Tercedor-Sánchez, Luis
A1 Abadia-Molina, Francisco
K1 Cardiovascular diseases
K1 Atherosclerosis
K1 Gut microbiota
K1 Microbiome
K1 Enfermedades cardiovasculares
K1 Aterosclerosis
K1 Microbioma gastrointestinal
K1 Microbiota
AB The importance of gut microbiota in health and disease is being highlighted by numerous research groups worldwide. Atherosclerosis, the leading cause of heart disease and stroke, is responsible for about 50% of all cardiovascular deaths. Recently, gut dysbiosis has been identified as a remarkable factor to be considered in the pathogenesis of cardiovascular diseases (CVDs). In this review, we briefly discuss how external factors such as dietary and physical activity habits influence host-microbiota and atherogenesis, the potential mechanisms of the influence of gut microbiota in host blood pressure and the alterations in the prevalence of those bacterial genera affecting vascular tone and the development of hypertension. We will also be examining the microbiota as a therapeutic target in the prevention of CVDs and the beneficial mechanisms of probiotic administration related to cardiovascular risks. All these new insights might lead to novel analysis and CVD therapeutics based on the microbiota.
PB MDPI
YR 2020
FD 2020-02-26
LK http://hdl.handle.net/10668/3611
UL http://hdl.handle.net/10668/3611
LA en
NO Sanchez-Rodriguez E, Egea-Zorrilla A, Plaza-Díaz J, Aragón-Vela J, Muñoz-Quezada S, Tercedor-Sánchez L, et al. The Gut Microbiota and Its Implication in the Development of Atherosclerosis and Related Cardiovascular Diseases. Nutrients. 2020 Feb 26;12(3):605
DS RISalud
RD Apr 9, 2025