TY  - JOUR
AU  - Nicastro, Raffaele
AU  - Gaillard, Hélène
AU  - Zarzuela, Laura
AU  - Péli-Gulli, Marie-Pierre
AU  - Fernández-García, Elisabet
AU  - Tomé, Mercedes
AU  - García-Rodríguez, Néstor
AU  - Durán, Raúl V
AU  - De Virgilio, Claudio
AU  - Wellinger, Ralf Erik
PY  - 2022
DO  - 10.7554/eLife.80497
UR  - http://hdl.handle.net/10668/21675
T2  - eLife
AB  - The essential biometal manganese (Mn) serves as a cofactor for several enzymes that are crucial for the prevention of human diseases. Whether intracellular Mn levels may be sensed and modulate intracellular signaling events has so far remained largely...
LA  - en
KW  - NRAMP transporter
KW  - S. cerevisiae
KW  - TORC1
KW  - autophagy
KW  - biochemistry
KW  - chemical biology
KW  - genetics
KW  - genomics
KW  - human
KW  - manganese
KW  - mitophagy
KW  - Adenosine Triphosphate
KW  - Animals
KW  - Humans
KW  - Mammals
KW  - Manganese
KW  - Mechanistic Target of Rapamycin Complex 1
KW  - Protein Kinases
KW  - Saccharomyces cerevisiae
KW  - Saccharomyces cerevisiae Proteins
TI  - Manganese is a physiologically relevant TORC1 activator in yeast and mammals.
TY  - research article
VL  - 11
ER  -