TY  - JOUR
AU  - Heras, Violeta
AU  - Sangiao-Alvarellos, Susana
AU  - Manfredi-Lozano, Maria
AU  - Sanchez-Tapia, María J
AU  - Ruiz-Pino, Francisco
AU  - Roa, Juan
AU  - Lara-Chica, Maribel
AU  - Morrugares-Carmona, Rosario
AU  - Jouy, Nathalie
AU  - Abreu, Ana P
AU  - Prevot, Vincent
AU  - Belsham, Denise
AU  - Vazquez, Maria J
AU  - Calzado, Marco A
AU  - Pinilla, Leonor
AU  - Gaytan, Francisco
AU  - Latronico, Ana C
AU  - Kaiser, Ursula B
AU  - Castellano, Juan M
AU  - Tena-Sempere, Manuel
PY  - 2019
DO  - 10.1371/journal.pbio.3000532
UR  - http://hdl.handle.net/10668/14651
T2  - PLoS biology
AB  - Mkrn3, the maternally imprinted gene encoding the makorin RING-finger protein-3, has recently emerged as putative pubertal repressor, as evidenced by central precocity caused by MKRN3 mutations in humans; yet, the molecular underpinnings of this key...
LA  - en
PB  - Public Library of Science
KW  - Rats
KW  - Sequence analysis, DNA
KW  - Sexual maturation
KW  - Ubiquitin-protein ligases
KW  - Animals
KW  - Binding sites
KW  - Cell line
KW  - Female
KW  - Gene expression regulation, developmental
KW  - Hypothalamus
KW  - Male
KW  - MicroRNAs
TI  - Hypothalamic miR-30 regulates puberty onset via repression of the puberty-suppressing factor, Mkrn3.
TY  - research article
VL  - 17
ER  -