TY  - JOUR
AU  - Jiménez-Vacas, Juan M.
AU  - Herrero-Aguayo, Vicente
AU  - Montero-Hidalgo, Antonio J.
AU  - Gómez-Gómez, Enrique
AU  - Fuentes-Fayos, Antonio C.
AU  - León-González, Antonio J.
AU  - Sáez-Martínez, Prudencio
AU  - Alors-Pérez, Emilia
AU  - Pedraza-Arévalo, Sergio
AU  - González-Serrano, Teresa
AU  - Reyes, Oscar
AU  - Martínez-López, Ana
AU  - Sánchez-Sánchez, Rafael
AU  - Ventura, Sebastián
AU  - Yubero-Serrano, Elena M.
AU  - Requena-Tapia, María J.
AU  - Castaño, Justo P.
AU  - Gahete, Manuel D.
AU  - Luque, Raúl M.
PY  - 2020
DO  - 10.1016/j.ebiom.2019.11.008
UR  - http://hdl.handle.net/10668/4392
T2  - EBioMedicine
AB  - Background: Dysregulation of splicing variants (SVs) expression has recently emerged as a novel cancer hallmark. Although the generation of aberrant SVs (e.g. AR-v7/sst5TMD4/etc.) is associated to prostate-cancer (PCa) aggressiveness and/or...
LA  - en
PB  - Elsevier
KW  - Prostate cancer
KW  - Splicing
KW  - Spliceosome
KW  - SNRNP200
KW  - SRSF3
KW  - SRRM1
KW  - Therapeutic target
KW  - Neoplasias de la próstata
KW  - Empalmosomas
KW  - Andalucía
KW  - ARN mensajero
KW  - Western blotting
KW  - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Benzamides
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Carcinogenesis::Cocarcinogenesis
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Growth Processes::Cell Proliferation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Gene Expression Regulation, Neoplastic
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic::Gene Silencing
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Check Tags::Male
KW  - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplastic Processes::Neoplasm Invasiveness
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Neoplasm Proteins
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Nitriles
KW  - Medical Subject Headings::Chemicals and Drugs::Heterocyclic Compounds::Heterocyclic Compounds, 1-Ring::Azoles::Imidazoles::Imidazolidines::Hydantoins::Thiohydantoins::Phenylthiohydantoin
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Urogenital Neoplasms::Genital Neoplasms, Male::Prostatic Neoplasms
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::RNA Processing, Post-Transcriptional::RNA Splicing
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cell Nucleus::Cell Nucleus Structures::Intranuclear Space::Spliceosomes
KW  - Medical Subject Headings::Geographical Locations::Geographic Locations::Europe::Spain
KW  - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleic Acids::RNA::RNA, Messenger::RNA, Messenger, Stored
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Immunologic Techniques::Immunoassay::Immunoblotting::Blotting, Western
TI  - Dysregulation of the splicing machinery is directly associated to aggressiveness of prostate cancer
TY  - research article
ER  -