RT Journal Article
T1 Development of atrioventricular and intraventricular conduction disturbances in patients undergoing transcatheter aortic valve replacement with new generation self-expanding valves: A real world multicenter analysis.
A1 Castro-Mejía, Alex F
A1 Amat-Santos, Ignacio
A1 Ortega-Armas, Maria E
A1 Baz, Jose A
A1 Moreno, Raúl
A1 Diaz, Jose F
A1 Travieso, Alejandro
A1 Jimenez-Quevedo, Pilar
A1 Santos-Martínez, Sandra
A1 McInerney, Angela
A1 Galeote, Guillermo
A1 Díaz, Victor Alfonso Jimenez
A1 Garrido, Jessica Roa
A1 Tirado-Conte, Gabriela
A1 Barrero, Alejandro
A1 Marroquin, Luis
A1 Nuñez-Gil, Ivan
A1 Gonzalo, Nieves
A1 Fernandez-Ortiz, Antonio
A1 Escaned, Javier
A1 Nombela-Franco, Luis
K1 Electrocardiographic disturbances
K1 Pacemaker
K1 Self-expanding aortic valves
K1 Transcatheter aortic valve replacement
AB High degree cardiac conduction disturbances (HDCD) remain a major complication after transcatheter aortic valve replacement (TAVR), especially with self-expandable valves (SEV). Our aim was to investigate peri-procedural and in-hospital modification of atrioventricular and intracardiac conduction associated to new generation SEV implantation, and the development of new HDCD resulting in permanent pacemaker implantation (PPM) in patients undergoing TAVR. Three-hundred forty-four consecutive patients with severe aortic stenosis who underwent TAVR with a new generation SEV [Evolut-R/Pro (n = 130), Acurate-neo (n = 79), Portico (n = 75) and Allegra (n = 60)] were included. An analysis of baseline, post-TAVR and pre-discharge ECG and procedural aspects were centrally performed. A significant increase in baseline PR interval (169.6 ± 28.2 ms) and QRS complex width (101.7 ± 25.9 ms) was noted immediately post-TAVR (188.04 ± 34.49; 129.55 ± 30.02 ms), with a partial in-hospital reversal (179.4 ± 30.1; 123.06 ± 30.94 ms), resulting in a net increase at hospital discharge of 12.6 ± 38.8 ms and 21.4 ± 31.6 ms (p  New generation self-expanding aortic valves were associated with a significant increase in PR and QRS interval at hospital discharge leading to a very high rate of HDCD. While valve recapture and implantation depth were independent predictors for the occurrence of HDCD, use of Accurate-Neo valve was a protective factor.
YR 2022
FD 2022-05-10
LK http://hdl.handle.net/10668/22263
UL http://hdl.handle.net/10668/22263
LA en
DS RISalud
RD Apr 5, 2025