TY - JOUR AU - Kopecka, Joanna AU - Salaroglio, Iris C AU - Perez-Ruiz, Elizabeth AU - Sarmento-Ribeiro, Ana Bela AU - Saponara, Simona AU - De Las Rivas, Javier AU - Riganti, Chiara PY - 2021 DO - 10.1016/j.drup.2021.100787 UR - https://hdl.handle.net/10668/26998 T2 - Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy AB - Hypoxia, a hallmark of solid tumors, determines the selection of invasive and aggressive malignant clones displaying resistance to radiotherapy, conventional chemotherapy or targeted therapy. The recent introduction of immunotherapy, based on immune... LA - en KW - CAR T-cells KW - Drug resistance KW - Immune checkpoint inhibitors KW - Tumor hypoxia KW - Humans KW - Hypoxia KW - Immunotherapy KW - Neoplasms KW - Tumor Microenvironment TI - Hypoxia as a driver of resistance to immunotherapy. TY - research article VL - 59 ER -