%0 Journal Article %A Deschasaux, Mélanie %A Huybrechts, Inge %A Murphy, Neil %A Julia, Chantal %A Hercberg, Serge %A Srour, Bernard %A Kesse-Guyot, Emmanuelle %A Latino-Martel, Paule %A Biessy, Carine %A Casagrande, Corinne %A Jenab, Mazda %A Ward, Heather %A Weiderpass, Elisabete %A Dahm, Christina C %A Overvad, Kim %A Kyrø, Cecilie %A Olsen, Anja %A Affret, Aurélie %A Boutron-Ruault, Marie-Christine %A Mahamat-Saleh, Yahya %A Kaaks, Rudolf %A Kühn, Tilman %A Boeing, Heiner %A Schwingshackl, Lukas %A Bamia, Christina %A Peppa, Eleni %A Trichopoulou, Antonia %A Masala, Giovanna %A Krogh, Vittorio %A Panico, Salvatore %A Tumino, Rosario %A Sacerdote, Carlotta %A Bueno-de-Mesquita, Bas %A Peeters, Petra H %A Hjartåker, Anette %A Rylander, Charlotta %A Skeie, Guri %A Ramón Quirós, J %A Jakszyn, Paula %A Salamanca-Fernández, Elena %A Huerta, José María %A Ardanaz, Eva %A Amiano, Pilar %A Ericson, Ulrika %A Sonestedt, Emily %A Huseinovic, Ena %A Johansson, Ingegerd %A Khaw, Kay-Tee %A Wareham, Nick %A Bradbury, Kathryn E %A Perez-Cornago, Aurora %A Tsilidis, Konstantinos K %A Ferrari, Pietro %A Riboli, Elio %A Gunter, Marc J %A Touvier, Mathilde %T Nutritional quality of food as represented by the FSAm-NPS nutrient profiling system underlying the Nutri-Score label and cancer risk in Europe: Results from the EPIC prospective cohort study. %D 2018 %U http://hdl.handle.net/10668/12960 %X Helping consumers make healthier food choices is a key issue for the prevention of cancer and other diseases. In many countries, political authorities are considering the implementation of a simplified labelling system to reflect the nutritional quality of food products. The Nutri-Score, a five-colour nutrition label, is derived from the Nutrient Profiling System of the British Food Standards Agency (modified version) (FSAm-NPS). How the consumption of foods with high/low FSAm-NPS relates to cancer risk has been studied in national/regional cohorts but has not been characterized in diverse European populations. This prospective analysis included 471,495 adults from the European Prospective Investigation into Cancer and Nutrition (EPIC, 1992-2014, median follow-up: 15.3 y), among whom there were 49,794 incident cancer cases (main locations: breast, n = 12,063; prostate, n = 6,745; colon-rectum, n = 5,806). Usual food intakes were assessed with standardized country-specific diet assessment methods. The FSAm-NPS was calculated for each food/beverage using their 100-g content in energy, sugar, saturated fatty acid, sodium, fibres, proteins, and fruits/vegetables/legumes/nuts. The FSAm-NPS scores of all food items usually consumed by a participant were averaged to obtain the individual FSAm-NPS Dietary Index (DI) scores. Multi-adjusted Cox proportional hazards models were computed. A higher FSAm-NPS DI score, reflecting a lower nutritional quality of the food consumed, was associated with a higher risk of total cancer (HRQ5 versus Q1 = 1.07; 95% CI 1.03-1.10, P-trend In this large multinational European cohort, the consumption of food products with a higher FSAm-NPS score (lower nutritional quality) was associated with a higher risk of cancer. This supports the relevance of the FSAm-NPS as underlying nutrient profiling system for front-of-pack nutrition labels, as well as for other public health nutritional measures. %~