RT Journal Article T1 New Insights in Therapy for Food Allergy A1 Mayorga, Cristobalina A1 Palomares, Francisca A1 Cañas, José A. A1 Pérez-Sánchez, Natalia A1 Núñez, Rafael A1 Torres, María José A1 Gómez, Francisca K1 Food allergy K1 Specific immunotherapy K1 Non-specific therapy K1 Hypoallergens K1 Nanoparticles K1 Microbiota K1 Hipersensibilidad a los alimentos K1 Inmunoterapia K1 Nanopartículas K1 Microbiota AB Food allergy is an increasing problem worldwide, with strict avoidance being classically the only available reliable treatment. The main objective of this review is to cover the latest information about the tools available for the diagnosis and treatment of food allergies. In recent years, many efforts have been made to better understand the humoral and cellular mechanisms involved in food allergy and to improve the strategies for diagnosis and treatment. This review illustrates IgE-mediated food hypersensitivity and provides a current description of the diagnostic strategies and advances in different treatments. Specific immunotherapy, including different routes of administration and new therapeutic approaches, such as hypoallergens and nanoparticles, are discussed in detail. Other treatments, such as biologics and microbiota, are also described. Therefore, we conclude that although important efforts have been made in improving therapies for food allergies, including innovative approaches mainly focusing on efficacy and safety, there is an urgent need to develop a set of basic and clinical results to help in the diagnosis and treatment of food allergies. PB MDPI YR 2021 FD 2021-05-10 LK http://hdl.handle.net/10668/3668 UL http://hdl.handle.net/10668/3668 LA en NO Mayorga C, Palomares F, Cañas JA, Pérez-Sánchez N, Núñez R, Torres MJ, et al. New Insights in Therapy for Food Allergy. Foods. 2021 May 10;10(5):1037 DS RISalud RD Apr 17, 2025