TY - JOUR AU - Maaser, Anna AU - Forstner, Andreas J AU - Strohmaier, Jana AU - Hecker, Julian AU - Ludwig, Kerstin U AU - Sivalingam, Sugirthan AU - Streit, Fabian AU - Degenhardt, Franziska AU - Witt, Stephanie H AU - Reinbold, Céline S AU - Koller, Anna C AU - Raff, Ruth AU - Heilmann-Heimbach, Stefanie AU - Fischer, Sascha B AU - Bipolar Disorder Working Group of the Psychiatric Genomics Consortium AU - Herms, Stefan AU - Hoffmann, Per AU - Thiele, Holger AU - Nürnberg, Peter AU - Löhlein Fier, Heide AU - Orozco-Díaz, Guillermo AU - Carmenate-Naranjo, Deinys AU - Proenza-Barzaga, Niurka AU - Auburger, Georg W J AU - Andlauer, Till F M AU - Cichon, Sven AU - Marcheco-Teruel, Beatriz AU - Mors, Ole AU - Rietschel, Marcella AU - Nöthen, Markus M PY - 2018 DO - 10.1371/journal.pone.0205895 UR - http://hdl.handle.net/10668/13142 T2 - PloS one AB - Bipolar disorder (BD) is a major psychiatric illness affecting around 1% of the global population. BD is characterized by recurrent manic and depressive episodes, and has an estimated heritability of around 70%. Research has identified the first BD... LA - en KW - Alleles KW - Bipolar Disorder KW - Complement C1 Inhibitor Protein KW - Cuba KW - Exome KW - Family KW - Female KW - Gene Expression KW - Gene Regulatory Networks KW - Genetic Predisposition to Disease KW - Genome-Wide Association Study KW - Humans KW - Male KW - Pedigree KW - Penetrance KW - Polymorphism, Single Nucleotide KW - Risk KW - Exome Sequencing TI - Exome sequencing in large, multiplex bipolar disorder families from Cuba. TY - research article VL - 13 ER -