TY - JOUR AU - Santucci, Matteo AU - Spyrakis, Francesca AU - Cross, Simon AU - Quotadamo, Antonio AU - Farina, Davide AU - Tondi, Donatella AU - De Luca, Filomena AU - Docquier, Jean-Denis AU - Prieto, Ana Isabel AU - Ibacache, Claudia AU - Blázquez, Jesús AU - Venturelli, Alberto AU - Cruciani, Gabriele AU - Costi, Maria Paola PY - 2017 DO - 10.1038/s41598-017-17399-7 UR - http://hdl.handle.net/10668/11925 T2 - Scientific reports AB - β-Lactamases (BLs) able to hydrolyze β-lactam antibiotics and more importantly the last resort carbapenems, represent a major mechanism of resistance in Gram-negative bacteria showing multi-drug or extensively drug resistant phenotypes. The early... LA - en KW - Anti-Bacterial Agents KW - Bacteria KW - Bacterial Proteins KW - Boronic Acids KW - Cefotaxime KW - Ceftazidime KW - Computational Biology KW - Drug Resistance, Bacterial KW - Enterobacteriaceae Infections KW - Microbial Sensitivity Tests KW - beta-Lactamase Inhibitors KW - beta-Lactamases TI - Computational and biological profile of boronic acids for the detection of bacterial serine- and metallo-β-lactamases. TY - research article VL - 7 ER -