TY  - JOUR
AU  - Hadwen, Jeremiah
AU  - Schock, Sarah
AU  - Farooq, Faraz
AU  - MacKenzie, Alex
AU  - Plaza-Diaz, Julio
PY  - 2021
DO  - 10.3390/ijms22126295
UR  - http://hdl.handle.net/10668/4479
T2  - International Journal of Molecular Sciences
AB  - The development of DNA microarray and RNA-sequencing technology has led to an explosion in the generation of transcriptomic differential expression data under a wide range of biologic systems including those recapitulating the monogenic muscular...
LA  - en
PB  - MDPI
KW  - Transcriptomics
KW  - Differential expression analysis
KW  - Rare diseases
KW  - Drug repurposing
KW  - Perfiles de expresión génica
KW  - Enfermedades raras
KW  - Nuevas indicaciones de medicamentos
KW  - Transcriptoma
KW  - Redes génicas reguladoras
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line::Cell Line, Tumor
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Down-Regulation
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid::Gene Regulatory Networks
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice::Mice, Inbred Strains::Mice, Inbred C57BL
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Base Sequence::Regulatory Sequences, Nucleic Acid
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Research Design::Reproducibility of Results
KW  - Medical Subject Headings::Chemicals and Drugs::Hormones, Hormone Substitutes, and Hormone Antagonists::Hormones::Thyroid Hormones::Thyroxine
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Transcriptome
KW  - Medical Subject Headings::Information Science::Information Science::Medical Informatics::Medical Informatics Applications::Information Systems::Databases as Topic::Databases, Factual::Databases, Genetic
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Rare Diseases
TI  - Separating the Wheat from the Chaff: The Use of Upstream Regulator Analysis to Identify True Differential Expression of Single Genes within Transcriptomic Datasets
TY  - research article
ER  -