TY - JOUR AU - Noriega, Víctor AU - Martínez-Laperche, Carolina AU - Buces, Elena AU - Pion, Marjorie AU - Sánchez-Hernández, Noemí AU - Martín-Antonio, Beatriz AU - Guillem, Vicent AU - Bosch-Vizcaya, Anna AU - Bento, Leyre AU - González-Rivera, Milagros AU - Balsalobre, Pascual AU - Kwon, Mi AU - Serrano, David AU - Gayoso, Jorge AU - de la Cámara, Rafael AU - Brunet, Salut AU - Rojas-Contreras, Rafael AU - Nieto, José B AU - Martínez, Carmen AU - Gónzalez, Marcos AU - Espigado, Ildefonso AU - Vallejo, Juan C AU - Sampol, Antonia AU - Jiménez-Velasco, Antonio AU - Urbano-Ispizua, Alvaro AU - Solano, Carlos AU - Gallardo, David AU - Díez-Martín, José L AU - Buño, Ismael PY - 2015 DO - 10.1371/journal.pone.0140454 UR - http://hdl.handle.net/10668/2284 T2 - PloS One AB - The FOXP3 gene encodes for a protein (Foxp3) involved in the development and functional activity of regulatory T cells (CD4+/CD25+/Foxp3+), which exert regulatory and suppressive roles over the immune system. After allogeneic stem cell... LA - en PB - Public Libray of Science KW - Anciano KW - Femenino KW - Adulto KW - Factores de transcripción en cabeza de tenedor KW - Estudios de asociación genética KW - Genotipo KW - Enfermedad injerto contra huésped KW - Efecto injerto contra leucemia KW - Trasplante de células madre hematopoyéticas KW - Humanos KW - Masculino KW - Mediana edad KW - Polimorfismo genético KW - Regiones promotoras genéticas KW - Análisis de supervivencia KW - Donantes de tejidos KW - Trasplante homólogo KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Transcription Factors::Winged-Helix Transcription Factors::Forkhead Transcription Factors KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Genetic Techniques::Genetic Association Studies KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genotype KW - Medical Subject Headings::Diseases::Immune System Diseases::Graft vs Host Disease KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immune System Processes::Transplantation Immunology::Graft vs Host Reaction::Graft vs Tumor Effect::Graft vs Leukemia Effect KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Cell Transplantation::Stem Cell Transplantation::Hematopoietic Stem Cell Transplantation KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Middle Aged KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Variation::Polymorphism, Genetic KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Structures::Genome::Genome Components::Genes::Gene Components::Regulatory Elements, Transcriptional::Promoter Regions, Genetic KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Statistics as Topic::Survival Analysis KW - Medical Subject Headings::Named Groups::Persons::Tissue Donors KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Surgical Procedures, Operative::Transplantation::Transplantation, Homologous KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult::Young Adult KW - Medical Subject Headings::Named Groups::Persons::Age Groups::Adult TI - The Genotype of the Donor for the (GT)n Polymorphism in the Promoter/Enhancer of FOXP3 Is Associated with the Development of Severe Acute GVHD but Does Not Affect the GVL Effect after Myeloablative HLA-Identical Allogeneic Stem Cell Transplantation. TY - research article ER -