TY  - JOUR
AU  - Tortajada, Agustín
AU  - Gutiérrez, Eduardo
AU  - Goicoechea de Jorge, Elena
AU  - Anter, Jaouad
AU  - Segarra, Alfons
AU  - Espinosa, Mario
AU  - Blasco, Miquel
AU  - Roman, Elena
AU  - Marco, Helena
AU  - Quintana, Luis F
AU  - Gutiérrez, Josué
AU  - Pinto, Sheila
AU  - Lopez-Trascasa, Margarita
AU  - Praga, Manuel
AU  - Rodriguez de Córdoba, Santiago
PY  - 2017
DO  - 10.1016/j.kint.2017.03.041
UR  - http://hdl.handle.net/10668/11330
T2  - Kidney international
AB  - IgA nephropathy (IgAN), a frequent cause of chronic kidney disease worldwide, is characterized by mesangial deposition of galactose-deficient IgA1-containing immune complexes. Complement involvement in IgAN pathogenesis is suggested by the glomerular...
LA  - en
KW  - CFH mutation
KW  - IgAN
KW  - complement alternative pathway
KW  - factor H
KW  - factor H-related proteins
KW  - Adult
KW  - Blood Proteins
KW  - Cohort Studies
KW  - Complement C3b Inactivator Proteins
KW  - Complement Factor H
KW  - Complement Pathway, Alternative
KW  - Disease Progression
KW  - Female
KW  - Glomerular Filtration Rate
KW  - Glomerulonephritis, IGA
KW  - Humans
KW  - Male
KW  - Middle Aged
KW  - Polycystic Kidney, Autosomal Dominant
KW  - Renal Insufficiency, Chronic
KW  - Young Adult
TI  - Elevated factor H-related protein 1 and factor H pathogenic variants decrease complement regulation in IgA nephropathy.
TY  - research article
VL  - 92
ER  -