TY - JOUR AU - Santiago-Fernández, Concepción AU - Pérez-Belmonte, Luis M. AU - Millán-Gómez, Mercedes AU - Moreno-Santos, Inmaculada AU - Carrasco-Chinchilla, Fernando AU - Ruiz-Salas, Amalio AU - Morcillo-Hidalgo, Luis AU - Melero, José M. AU - Garrido-Sánchez, Lourdes AU - Jiménez-Navarro, Manuel PY - 2019 DO - 10.1186/s12967-019-1842-2 UR - http://hdl.handle.net/10668/3191 T2 - Journal of Translational Medicine AB - Background: Oxidized low-density lipoproteins and scavenger receptors (SRs) play an important role in the formation and development of atherosclerotic plaques. However, little is known about their presence in epicardial adipose tissue (EAT). The... LA - en PB - BioMed Central Ltd. KW - Scavenger receptors KW - Oxidized low-density KW - Epicardial adipose tissue KW - Diabetes mellitus KW - Ischemic heart disease KW - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Aged KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Epidemiologic Methods::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Case-Control Studies KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Movement KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia::Coronary Disease::Coronary Artery Disease KW - Medical Subject Headings::Diseases::Endocrine System Diseases::Diabetes Mellitus::Diabetes Mellitus, Type 2 KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Cardiomyopathies::Diabetic Cardiomyopathies KW - Medical Subject Headings::Check Tags::Female KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Lipids::Lipoproteins::Lipoproteins, LDL KW - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Macrophages KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Persons::Persons::Age Groups::Adult::Middle Aged KW - Medical Subject Headings::Diseases::Cardiovascular Diseases::Heart Diseases::Myocardial Ischemia KW - Medical Subject Headings::Anatomy::Cardiovascular System::Heart::Pericardium KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Scavenger KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Up-Regulation TI - Overexpression of scavenger receptor and infiltration of macrophage in epicardial adipose tissue of patients with ischemic heart disease and diabetes TY - research article ER -