TY - JOUR AU - Serrano, César AU - García-Del-Muro, Xavier AU - Valverde, Claudia AU - Sebio, Ana AU - Durán, José AU - Manzano, Aránzazu AU - Pajares, Isabel AU - Hindi, Nadia AU - Landolfi, Stefania AU - Jiménez, Laura AU - Rubió-Casadevall, Jordi AU - Estival, Anna AU - Lavernia, Javier AU - Safont, María José AU - Pericay, Carles AU - Díaz-Beveridge, Roberto AU - Martínez-Marín, Virginia AU - Vicente-Baz, David AU - Vivancos, Ana AU - Hernández-Losa, Javier AU - Arribas, Joaquín AU - Carles, Joan PY - 2018 DO - 10.1634/theoncologist.2018-0032 UR - http://hdl.handle.net/10668/12858 T2 - The oncologist AB - Oncogenic KIT/PDGFRA signaling inhibition with imatinib achieves disease control in most patients with advanced/metastatic gastrointestinal stromal tumor (GIST), but resistance eventually develops after 20-24 months. Notably, a small subset of these... LA - en KW - Gastrointestinal stromal tumor KW - Imatinib mesylate KW - Long‐term KW - c‐KIT KW - Adult KW - Antineoplastic Agents KW - Case-Control Studies KW - Disease Progression KW - Drug Resistance, Neoplasm KW - Female KW - Gastrointestinal Neoplasms KW - Gastrointestinal Stromal Tumors KW - Humans KW - Imatinib Mesylate KW - Male KW - Middle Aged KW - Prognosis KW - Progression-Free Survival KW - Sarcoma KW - Time Factors TI - Clinicopathological and Molecular Characterization of Metastatic Gastrointestinal Stromal Tumors with Prolonged Benefit to Frontline Imatinib. TY - research article VL - 24 ER -