TY - JOUR AU - Guzman-Parra, Jose AU - Streit, Fabian AU - Forstner, Andreas J AU - Strohmaier, Jana AU - Gonzalez, Maria Jose AU - Gil- Flores, Susana AU - Cabaleiro-Fabeiro, Francisco J AU - Del-Rio-Noriega, Francisco AU - Perez- Perez, Fermin AU - Haro-Gonzalez, Jesus AU - Orozco-Diaz, Guillermo AU - de-Diego-Otero, Yolanda AU - Moreno-Kustner, Berta AU - Auburger, Georg AU - Degenhardt, Franziska AU - Heilmann-Heimbach, Stefanie AU - Herms, Stefan AU - Hoffmann, Per AU - Frank, Josef AU - Foo, Jerome C AU - Sirignano, Lea AU - Witt, Stephanie H AU - Cichon, Sven AU - Rivas, Fabio AU - Mayoral, Fermin AU - Nothen, Markus M AU - Andlauer, Till F M AU - Rietschel, Marcella PY - 2021 DO - 10.1038/s41398-020-01146-0 UR - http://hdl.handle.net/10668/16959 T2 - Translational psychiatry AB - The two major subtypes of bipolar disorder (BD), BD-I and BD-II, are distinguished based on the presence of manic or hypomanic episodes. Historically, BD-II was perceived as a less severe form of BD-I. Recent research has challenged this concept of a... LA - en PB - Nature Publishing Group KW - Área de Gestión Sanitaria Campo de Gibraltar Oeste KW - Área de Gestión Sanitaria de Jerez, Costa Noroeste y Sierra de Cádiz KW - Depression KW - Disease Progression KW - Suicidal Ideation KW - Bipolar Disorder KW - Bipolar Disorder KW - Humans KW - Multifactorial Inheritance KW - Risk Factors KW - Schizophrenia KW - Suicidal Ideation TI - Clinical and genetic differences between bipolar disorder type 1 and 2 in multiplex families. TY - research article VL - 11 ER -