TY - JOUR AU - Yeste, Ada AU - Takenaka, Maisa C AU - Mascanfroni, Ivan D AU - Nadeau, Meghan AU - Kenison, Jessica E AU - Patel, Bonny AU - Tukpah, Ann-Marcia AU - Babon, Jenny Aurielle B AU - DeNicola, Megan AU - Kent, Sally C AU - Pozo, David AU - Quintana, Francisco J PY - 2016 DO - 10.1126/scisignal.aad0612 UR - http://hdl.handle.net/10668/10203 T2 - Science signaling AB - Type 1 diabetes (T1D) is a T cell-dependent autoimmune disease that is characterized by the destruction of insulin-producing β cells in the pancreas. The administration to patients of ex vivo-differentiated FoxP3(+) regulatory T (Treg) cells or... LA - en KW - Animals KW - Basic Helix-Loop-Helix Transcription Factors KW - Diabetes Mellitus, Type 1 KW - Humans KW - Indoles KW - Insulin-Secreting Cells KW - Mice, Inbred NOD KW - Nanoparticles KW - Receptors, Aryl Hydrocarbon KW - Suppressor of Cytokine Signaling Proteins KW - T-Lymphocytes, Regulatory KW - Thiazoles TI - Tolerogenic nanoparticles inhibit T cell-mediated autoimmunity through SOCS2. TY - research article VL - 9 ER -