RT Conference Proceedings T1 Prognostic value of a high level of circulating endothelial cells in patients with HER2-recurrent or metastatic breast cancer treated with bevacizumab in combination with paclitaxel and gemcitabine as fi rst-line therapy A1 Manso, L A1 Ciruelos, E A1 Codes, M A1 De la Haba, J A1 Galan, A A1 Baena, J A1 Jaen, A A1 Gil, M A1 Murias, A A1 Blancas, I A1 Gonzalez, E A1 Perez, D A1 Bayo, JL A1 Mel, J A1 Garcia-Martinez, E A1 Cubedo, R A1 Salvador, J K1 Neoplasias K1 Bevacizumab K1 Anticuerpos monoclonales humanizados K1 Desoxicitidina K1 Progresión de la enfermedad K1 Células endoteliales K1 Paclitaxel AB Circulating endothelial cells (CECs) are shed from vessels and enter the circulation reflecting endothelial damage. Increased numbers of CECs have been documented in cancer, and appear to correlate with progression of the tumor. Bevacizumab (B) in combination with CT improves progression-free survival (PFS) of first-line treatments and may modify tumor cell intravasation and CEC/CTC levels. PB BioMed Central SN 1465-5411 YR 2011 FD 2011-11-16 LK http://hdl.handle.net/10668/2231 UL http://hdl.handle.net/10668/2231 LA en NO Manso L, Ciruelos E, Codes M, De la Haba J, Galan A, Baena J, et al. Prognostic value of a high level of circulating endothelial cells in patients with HER2-recurrent or metastatic breast cancer treated with bevacizumab in combination with paclitaxel and gemcitabine as fi rst-line therapy. Breast Cancer Res. 2011; 13(Suppl 2): P4. DS RISalud RD Apr 10, 2025