TY - JOUR AU - Han, Seong-Su AU - Wen, Kuo-Kuang AU - García-Rubio, María L AU - Wold, Marc S AU - Aguilera, Andrés AU - Niedzwiedz, Wojciech AU - Vyas, Yatin M PY - 2022 DO - 10.1038/s41467-022-31415-z UR - http://hdl.handle.net/10668/19539 T2 - Nature communications AB - Perturbation in the replication-stress response (RSR) and DNA-damage response (DDR) causes genomic instability. Genomic instability occurs in Wiskott-Aldrich syndrome (WAS), a primary immunodeficiency disorder, yet the mechanism remains largely... LA - en KW - Animals KW - Antigens, Surface KW - DNA Breaks, Double-Stranded KW - DNA Repair KW - DNA Replication KW - DNA, Single-Stranded KW - DNA-Binding Proteins KW - Genomic Instability KW - Humans KW - Protein Binding KW - Replication Protein A KW - Saccharomyces cerevisiae KW - Saccharomyces cerevisiae Proteins KW - Wiskott-Aldrich Syndrome Protein TI - WASp modulates RPA function on single-stranded DNA in response to replication stress and DNA damage. TY - research article VL - 13 ER -