TY - JOUR AU - Roboz, Gail J AU - Montesinos, Pau AU - Selleslag, Dominik AU - Wei, Andrew AU - Jang, Jun-Ho AU - Falantes, Jose AU - Voso, Maria T AU - Sayar, Hamid AU - Porkka, Kimmo AU - Marlton, Paula AU - Almeida, Antonio AU - Mohan, Sanjay AU - Ravandi, Farhad AU - Garcia-Manero, Guillermo AU - Skikne, Barry AU - Kantarjian, Hagop PY - 2016 DO - 10.2217/fon.15.326 UR - http://hdl.handle.net/10668/9745 T2 - Future oncology (London, England) AB - Older patients with acute myeloid leukemia (AML) have worse rates of complete remission and shorter overall survival than younger patients. The epigenetic modifier CC-486 is an oral formulation of azacitidine with promising clinical activity in... LA - en KW - CC-486 KW - Phase III KW - acute myeloid leukemia KW - de novo KW - elderly KW - maintenance therapy KW - oral azacitidine KW - secondary KW - Administration, Oral KW - Antimetabolites, Antineoplastic KW - Azacitidine KW - Clinical Trials, Phase III as Topic KW - Humans KW - Leukemia, Myeloid, Acute KW - Maintenance Chemotherapy KW - Middle Aged KW - Randomized Controlled Trials as Topic TI - Design of the randomized, Phase III, QUAZAR AML Maintenance trial of CC-486 (oral azacitidine) maintenance therapy in acute myeloid leukemia. TY - research article VL - 12 ER -