RT Journal Article
RT null
T1 Respiratory syncytial virus outbreak in a tertiary hospital Neonatal Intensive Care Unit
A1 Moreno Parejo, Carlos
A1 Morillo Garcia, Aurea
A1 Lozano Dominguez, Carmen
A1 Carreno Ochoa, Concepcion
A1 Aznar Martin, Javier
A1 Conde Herrera, Manuel
K1 Respiratory syncytial viruses
K1 Cross infection
K1 Disease outbreaks
K1 Intensive care, neonatal
K1 Hand hygiene
K1 Rsv outbreak
K1 Infections
AB Introduction: Investigation and control of a respiratory syncytial virus (RSV) outbreak that affected the Neonatal Intensive Care Unit (NICU) of a university hospital from October to December 2012.Patients and methods: Cohort study of children admitted to the NICU. The infection attack rate was calculated. A descriptive analysis of the cases and a multivariate analysis was performed using the variables that were shown to be risk factors for RSV infection. Preventive measures taken were: contact isolation; hand hygiene training and observation; exclusivity of a health team of nurses and physicians for positive cases, restrictions on visitor numbers; surveillance RSV testing, and palivizumab prophylaxis.Results: The outbreak had three epidemic waves and 20 positive cases out of a total of 48 children admitted. The overall attack rate was 42%. Half of positive cases were children, with a median age of 36 days (p25 = 22, p75 = 58). The independent risk factors for RSV infection were birth weight below 1000 grams (OR = 23.5; P=.002) and to have another nosocomial infection the week before the diagnosis of RSV infection (OR = 19.98; P=.016).Conclusions: It was an outbreak with a high number of cases, due to the delay in notification, prolonged RSV carrier status, and low adherence to hand hygiene practice, which favoured the cross-transmission of infection. The most effective preventive measures were direct observation of hand hygiene and supervision of isolation measures. (C) 2015 Asociacion Espanola de Pediatria. Published by Elsevier Espana, S.L.U. All rights reserved.
PB Ediciones doyma s a
SN 1695-4033
YR 2016
FD 2016-09-01
LK http://hdl.handle.net/10668/18677
UL http://hdl.handle.net/10668/18677
LA es
DS RISalud
RD Apr 6, 2025