TY - JOUR AU - Rodríguez-Hernández, María A AU - González, Raúl AU - de la Rosa, Ángel J AU - Gallego, Paloma AU - Ordóñez, Raquel AU - Navarro-Villarán, Elena AU - Contreras, Laura AU - Rodríguez-Arribas, Mario AU - González-Gallego, Javier AU - Álamo-Martínez, José M AU - Marín-Gómez, Luís M AU - Del Campo, José A AU - Quiles, José L AU - Fuentes, José M AU - de la Cruz, Jesús AU - Mauriz, José L AU - Padillo, Francisco J AU - Muntané, Jordi PY - 2018 DO - 10.1002/jcp.26855 UR - http://hdl.handle.net/10668/12863 T2 - Journal of cellular physiology AB - Sorafenib is the unique accepted molecular targeted drug for the treatment of patients in advanced stage of hepatocellular carcinoma. The current study evaluated cell signaling regulation of endoplasmic reticulum (ER) stress, c-Jun-N-terminal kinase... LA - en KW - 5′AMP-activated protein kinase (AMPK) KW - Bcl-2 KW - apoptosis KW - autophagy KW - endoplasmic reticulum stress KW - mammalian target of rapamycin (mTOR) KW - Animals KW - Apoptosis KW - Autophagy KW - Biomarkers, Tumor KW - Caspase 3 KW - Endoplasmic Reticulum Stress KW - Gene Expression Regulation, Neoplastic KW - Hep G2 Cells KW - Humans KW - JNK Mitogen-Activated Protein Kinases KW - Liver Neoplasms KW - Mice KW - Myeloid Cell Leukemia Sequence 1 Protein KW - Neoplasm Proteins KW - Signal Transduction KW - Sorafenib KW - Transcription Factor CHOP KW - Xenograft Model Antitumor Assays TI - Molecular characterization of autophagic and apoptotic signaling induced by sorafenib in liver cancer cells. TY - research article VL - 234 ER -