RT Journal Article
T1 Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic from Euvolemic Hyponatremia.
A1 Ruiz-Sánchez, Jorge Gabriel
A1 Cuesta, Martín
A1 Gómez-Hoyos, Emilia
A1 Cárdenas-Salas, Jersy
A1 Rubio-Herrera, Miguel Ángel
A1 Martínez-González, Estefanía
A1 De Miguel Novoa, Paz
A1 Ternero-Vega, Jara Eloisa
A1 Calle-Pascual, Alfonso Luis
A1 Runkle, Isabelle
K1 SIAD
K1 euvolemic hyponatremia
K1 hyponatremia
K1 hypovolemic hyponatremia
K1 serum creatinine
AB Background and Objectives: Differentiating between hypovolemic (HH) and euvolemic hyponatremia (EH) is crucial for correct diagnosis and therapy, but can be a challenge. We aim to ascertain whether changes in serum creatinine (SC) can be helpful in distinguishing HH from EH. Materials and Methods: Retrospective analysis of patients followed in a monographic hyponatremia outpatient clinic of a tertiary hospital during 1 January 2014−30 November 2019. SC changes during HH and EH from eunatremia were studied. The diagnostic accuracy of the SC change from eunatremia to hyponatremia (∆SC) was analyzed. Results: A total of 122 hyponatremic patients, median age 79 years (70−85), 46.7% women. In total, 70/122 patients had EH, 52/122 HH. During hyponatremia, median SC levels increased in the HH group: +0.18 mg/dL [0.09−0.39, p
YR 2022
FD 2022-06-25
LK http://hdl.handle.net/10668/21426
UL http://hdl.handle.net/10668/21426
LA en
DS RISalud
RD Apr 18, 2025