%0 Journal Article
%A Ruiz-Sánchez, Jorge Gabriel
%A Cuesta, Martín
%A Gómez-Hoyos, Emilia
%A Cárdenas-Salas, Jersy
%A Rubio-Herrera, Miguel Ángel
%A Martínez-González, Estefanía
%A De Miguel Novoa, Paz
%A Ternero-Vega, Jara Eloisa
%A Calle-Pascual, Alfonso Luis
%A Runkle, Isabelle
%T Changes in Serum Creatinine Levels Can Help Distinguish Hypovolemic from Euvolemic Hyponatremia.
%D 2022
%U http://hdl.handle.net/10668/21426
%X Background and Objectives: Differentiating between hypovolemic (HH) and euvolemic hyponatremia (EH) is crucial for correct diagnosis and therapy, but can be a challenge. We aim to ascertain whether changes in serum creatinine (SC) can be helpful in distinguishing HH from EH. Materials and Methods: Retrospective analysis of patients followed in a monographic hyponatremia outpatient clinic of a tertiary hospital during 1 January 2014−30 November 2019. SC changes during HH and EH from eunatremia were studied. The diagnostic accuracy of the SC change from eunatremia to hyponatremia (∆SC) was analyzed. Results: A total of 122 hyponatremic patients, median age 79 years (70−85), 46.7% women. In total, 70/122 patients had EH, 52/122 HH. During hyponatremia, median SC levels increased in the HH group: +0.18 mg/dL [0.09−0.39, p
%K SIAD
%K euvolemic hyponatremia
%K hyponatremia
%K hypovolemic hyponatremia
%K serum creatinine
%~