RT Journal Article
T1 The first wave of the COVID-19 epidemic in Spain was associated with early introductions and fast spread of a dominating genetic variant.
A1 López, Mariana G
A1 Chiner-Oms, Álvaro
A1 García de Viedma, Darío
A1 Ruiz-Rodriguez, Paula
A1 Bracho, Maria Alma
A1 Cancino-Muñoz, Irving
A1 D'Auria, Giuseppe
A1 de Marco, Griselda
A1 García-González, Neris
A1 Goig, Galo Adrian
A1 Gómez-Navarro, Inmaculada
A1 Jiménez-Serrano, Santiago
A1 Martinez-Priego, Llúcia
A1 Ruiz-Hueso, Paula
A1 Ruiz-Roldán, Lidia
A1 Torres-Puente, Manuela
A1 Alberola, Juan
A1 Albert, Eliseo
A1 Aranzamendi Zaldumbide, Maitane
A1 Bea-Escudero, María Pilar
A1 Boga, Jose Antonio
A1 Bordoy, Antoni E
A1 Canut-Blasco, Andrés
A1 Carvajal, Ana
A1 Cilla Eguiluz, Gustavo
A1 Cordón Rodríguez, Maria Luz
A1 Costa-Alcalde, José J
A1 de Toro, María
A1 de Toro Peinado, Inmaculada
A1 Del Pozo, Jose Luis
A1 Duchêne, Sebastián
A1 Fernández-Pinero, Jovita
A1 Fuster Escrivá, Begoña
A1 Gimeno Cardona, Concepción
A1 González Galán, Verónica
A1 Gonzalo Jiménez, Nieves
A1 Hernáez Crespo, Silvia
A1 Herranz, Marta
A1 Lepe, José Antonio
A1 López-Causapé, Carla
A1 López-Hontangas, José Luis
A1 Martín, Vicente
A1 Martró, Elisa
A1 Milagro Beamonte, Ana
A1 Montes Ros, Milagrosa
A1 Moreno-Muñoz, Rosario
A1 Navarro, David
A1 Navarro-Marí, José María
A1 Not, Anna
A1 Oliver, Antonio
A1 Palop-Borrás, Begoña
A1 Parra Grande, Mónica
A1 Pedrosa-Corral, Irene
A1 Pérez González, Maria Carmen
A1 Pérez-Lago, Laura
A1 Pérez-Ruiz, Mercedes
A1 Piñeiro Vázquez, Luis
A1 Rabella, Nuria
A1 Rezusta, Antonio
A1 Robles Fonseca, Lorena
A1 Rodríguez-Villodres, Ángel
A1 Sanbonmatsu-Gámez, Sara
A1 Sicilia, Jon
A1 Soriano, Alex
A1 Tirado Balaguer, María Dolores
A1 Torres, Ignacio
A1 Tristancho, Alexander
A1 Marimón, José María
A1 SeqCOVID-Spain consortium, 
A1 Coscolla, Mireia
A1 González-Candelas, Fernando
A1 Comas, Iñaki
AB The coronavirus disease 2019 (COVID-19) pandemic has affected the world radically since 2020. Spain was one of the European countries with the highest incidence during the first wave. As a part of a consortium to monitor and study the evolution of the epidemic, we sequenced 2,170 samples, diagnosed mostly before lockdown measures. Here, we identified at least 500 introductions from multiple international sources and documented the early rise of two dominant Spanish epidemic clades (SECs), probably amplified by superspreading events. Both SECs were related closely to the initial Asian variants of SARS-CoV-2 and spread widely across Spain. We inferred a substantial reduction in the effective reproductive number of both SECs due to public-health interventions (Re 
YR 2021
FD 2021-09-30
LK https://hdl.handle.net/10668/26458
UL https://hdl.handle.net/10668/26458
LA en
DS RISalud
RD Apr 12, 2025