TY - JOUR AU - Crespo-Facorro, Benedicto AU - Ruiz-Veguilla, Miguel AU - Vázquez-Bourgon, Javier AU - Sánchez-Hidalgo, Ana C. AU - Garrido-Torres, Nathalia AU - Cisneros, Jose M. AU - Prieto, Carlos AU - Sainz, Jesus PY - 2021 DO - 10.3389/fphar.2021.646701 UR - http://hdl.handle.net/10668/4300 T2 - Frontiers in Pharmacology AB - Background: Antipsychotics modulate expression of inflammatory cytokines and inducible inflammatory enzymes. Elopiprazole (a phenylpiperazine antipsychotic drug in phase 1) has been characterized as a therapeutic drug to treat SARS-CoV-2 infection in... LA - en PB - Frontiers KW - Psychosis KW - Inflammation KW - Immunology KW - Coronavirus KW - Repurposing drugs KW - Elopiprazole KW - SARS-CoV-2 KW - Trastornos psicóticos KW - Inflamación KW - Alergia e inmunología KW - Nuevas indicaciones de medicamentos KW - Inmunidad KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Physiological Effects of Drugs::Central Nervous System Depressants::Tranquilizing Agents::Antipsychotic Agents KW - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression::Transcription, Genetic::Transcriptome KW - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Drug Discovery::Drug Repositioning KW - Medical Subject Headings::Psychiatry and Psychology::Mental Disorders::Schizophrenia and Disorders with Psychotic Features::Psychotic Disorders KW - Medical Subject Headings::Chemicals and Drugs::Biological Factors::Intercellular Signaling Peptides and Proteins::Cytokines KW - Medical Subject Headings::Diseases::Digestive System Diseases::Gastrointestinal Diseases::Intestinal Diseases::Inflammatory Bowel Diseases KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Cell Differentiation KW - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Antigen::Receptors, Antigen, B-Cell KW - Medical Subject Headings::Phenomena and Processes::Immune System Phenomena::Immunity TI - Aripiprazole as a Candidate Treatment of COVID-19 Identified Through Genomic Analysis TY - research article ER -