TY  - JOUR
AU  - Vendrell, Joan
AU  - Maymó-Masip, Elsa
AU  - Tinahones, Francisco J
AU  - García-España, Antonio
AU  - Megía, Ana
AU  - Caubet, Enric
AU  - García-Fuentes, Eduardo
AU  - Chacón, Matilde R
PY  - 2010
DO  - 10.1210/jc.2009-2481
SN  - 0021-972X
UR  - http://hdl.handle.net/10668/750
T2  - The Journal of Clinical Endocrinology And Metabolism
AB  - CONTEXTAdipose tissue hypoxia and endoplasmic reticulum (ER) stress may link the presence of chronic inflammation and macrophage infiltration in severely obese subjects. We previously reported the up-regulation of TNF-like weak inducer of apoptosis...
LA  - en
PB  - The Endocrine Society
KW  - TNFSF12 protein, human
KW  - TWEAK receptor
KW  - Tejido Adiposo
KW  - Biopsia
KW  - Western Blotting
KW  - Línea Celular
KW  - Estudios de Cohortes
KW  - Citocinas
KW  - Diabetes Mellitus Tipo 2
KW  - Retículo Endoplásmico
KW  - Expresión Génica
KW  - Inflamación
KW  - Macrófagos
KW  - Obesidad Mórbida
KW  - Receptores del Factor de Necrosis Tumoral
KW  - Transducción de Señal
KW  - Factores de Necrosis Tumoral
KW  - Regulación hacia Arriba
KW  - Adipocitos
KW  - Anoxia
KW  - Medical Subject Headings::Anatomy::Tissues::Connective Tissue::Adipose Tissue
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Respiratory::Anoxia
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Diagnosis::Diagnostic Techniques and Procedures::Diagnostic Techniques, Surgical::Biopsy
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Investigative Techniques::Chemistry Techniques, Analytical::Electrophoresis::Blotting, Western
KW  - Medical Subject Headings::Anatomy::Cells::Cells, Cultured::Cell Line
KW  - Medical Subject Headings::Health Care::Health Care Quality, Access, and Evaluation::Quality of Health Care::Health Care Evaluation Mechanisms::Epidemiologic Study Characteristics as Topic::Epidemiologic Studies::Cohort Studies
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Metabolic Diseases::Glucose Metabolism Disorders::Diabetes Mellitus::Diabetes Mellitus, Type 2
KW  - Medical Subject Headings::Anatomy::Cells::Cellular Structures::Intracellular Space::Cytoplasm::Cytoplasmic Structures::Organelles::Endoplasmic Reticulum
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Macrophages
KW  - Medical Subject Headings::Diseases::Nutritional and Metabolic Diseases::Nutrition Disorders::Overnutrition::Obesity::Obesity, Morbid
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, Immunologic::Receptors, Cytokine::Receptors, Tumor Necrosis Factor
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Signal Transduction
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Peptides::Intercellular Signaling Peptides and Proteins::Cytokines::Tumor Necrosis Factors
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Up-Regulation
KW  - Medical Subject Headings::Anatomy::Cells::Connective Tissue Cells::Adipocytes
TI  - Tumor necrosis-like weak inducer of apoptosis as a proinflammatory cytokine in human adipocyte cells: up-regulation in severe obesity is mediated by inflammation but not hypoxia.
TY  - research article
ER  -