TY - JOUR AU - Serrano-Pozo, Alberto AU - Sanchez-Garcia, Manuel A AU - Heras-Garvin, Antonio AU - March-Diaz, Rosana AU - Navarro, Victoria AU - Vizuete, Marisa AU - Lopez-Barneo, Jose AU - Vitorica, Javier AU - Pascual, Alberto PY - 2017 DO - 10.1371/journal.pone.0170345 UR - http://hdl.handle.net/10668/10784 T2 - PloS one AB - Recent epidemiological evidence has linked hypoxia with the development of Alzheimer disease (AD). A number of in vitro and in vivo studies have reported that hypoxia can induce amyloid-β peptide accumulation through various molecular mechanisms... LA - en PB - Public Library of Science KW - Alzheimer Disease KW - Amyloid beta-Peptides KW - Aspartic Acid Endopeptidases KW - Hypoxia-Inducible Factor 1, alpha Subunit KW - Mice, Transgenic KW - Real-Time Polymerase Chain Reaction KW - Amyloid Precursor Protein Secretases KW - Animals KW - Brain KW - Enzyme-Linked Immunosorbent Assay KW - Hypoxia KW - Mice KW - Mice, Inbred C57BL KW - RNA, Messenger KW - Transcription, Genetic TI - Acute and Chronic Sustained Hypoxia Do Not Substantially Regulate Amyloid-β Peptide Generation In Vivo. TY - research article VL - 12 ER -