TY  - JOUR
AU  - Thijssen, Rachel
AU  - Ter Burg, Johanna
AU  - Garrick, Brett
AU  - van Bochove, Gregor G W
AU  - Brown, Jennifer R
AU  - Fernandes, Stacey M
AU  - Rodríguez, María Solé
AU  - Michot, Jean-Marie
AU  - Hallek, Michael
AU  - Eichhorst, Barbara
AU  - Reinhardt, Hans Christian
AU  - Bendell, Johanna
AU  - Derks, Ingrid A M
AU  - van Kampen, Roel J W
AU  - Hege, Kristen
AU  - Kersten, Marie José
AU  - Trowe, Torsten
AU  - Filvaroff, Ellen H
AU  - Eldering, Eric
AU  - Kater, Arnon P
PY  - 2016
DO  - 10.1182/blood-2016-02-700328
UR  - http://hdl.handle.net/10668/10133
T2  - Blood
AB  - Inhibition of B-cell receptor (BCR) signaling pathways in chronic lymphocytic leukemia (CLL) provides significant clinical benefit to patients, mainly by blocking adhesion of CLL cells in the lymph node microenvironment. The currently applied...
LA  - en
KW  - Bridged Bicyclo Compounds, Heterocyclic
KW  - DNA-Activated Protein Kinase
KW  - Drug Resistance, Neoplasm
KW  - Female
KW  - Humans
KW  - Leukemia, Lymphocytic, Chronic, B-Cell
KW  - Male
KW  - Neoplasm Proteins
KW  - Nuclear Proteins
KW  - Purines
KW  - Pyrazines
KW  - Quinazolinones
KW  - Sulfonamides
KW  - TOR Serine-Threonine Kinases
KW  - Triazoles
KW  - Tumor Cells, Cultured
KW  - Vidarabine
TI  - Dual TORK/DNA-PK inhibition blocks critical signaling pathways in chronic lymphocytic leukemia.
TY  - research article
VL  - 128
ER  -