TY  - JOUR
AU  - Caballano-Infantes, Estefanía
AU  - Díaz, Irene
AU  - Hitos, Ana Belén
AU  - Cahuana, Gladys Margot
AU  - Martínez-Ruiz, Antonio
AU  - Soria-Juan, Bárbara
AU  - Rodríguez-Griñolo, Rosario
AU  - Hmadcha, Abdelkrim
AU  - Martín, Franz
AU  - Soria, Bernat
AU  - Tejedo, Juan R.
AU  - Bedoya, Francisco Javier
PY  - 2021
DO  - 10.3390/antiox10091408
UR  - http://hdl.handle.net/10668/4473
T2  - Antioxidants
AB  - The optimization of conditions to promote the stemness of pluripotent cells in vitro is instrumental for their use in advanced therapies. We show here that exposure of human iPSCs and human ESCs to low concentrations of the chemical NO donor DETA/NO...
LA  - en
PB  - MDPI
KW  - Pluripotency
KW  - Normoxia
KW  - Nitric oxide
KW  - Hypoxia
KW  - Metabolism
KW  - Hydroxylation
KW  - Mitochondria
KW  - Mitochondrial membranes
KW  - Proteasome inhibitor
KW  - Oxygen consumption
KW  - Glycolysis
KW  - Pluripotent stem cells
KW  - Óxido nítrico
KW  - Hipoxia
KW  - Metabolismo
KW  - Hidroxilación
KW  - Mitocondrias
KW  - Membranas mitocondriales
KW  - Inhibidores de proteasoma
KW  - Consumo de oxígeno
KW  - Glucólisis
KW  - Células madre pluripotentes
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Amides::Benzamides::DEET
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Hydroxylation
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Energy Metabolism::Proton-Motive Force::Membrane Potential, Mitochondrial
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Mitochondrial Turnover::Mitochondrial Dynamics
KW  - Medical Subject Headings::Chemicals and Drugs::Macromolecular Substances::Multiprotein Complexes::Multienzyme Complexes::Proteasome Endopeptidase Complex
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Oxygen Consumption
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolome
KW  - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Carbohydrate Metabolism::Glycolysis
KW  - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::DNA-Binding Proteins::Basic Helix-Loop-Helix Transcription Factors
KW  - Medical Subject Headings::Anatomy::Cells::Stem Cells::Pluripotent Stem Cells
KW  - Medical Subject Headings::Chemicals and Drugs::Inorganic Chemicals::Free Radicals::Nitric Oxide
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Signs and Symptoms::Signs and Symptoms, Respiratory::Anoxia
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism
KW  - Medical Subject Headings::Phenomena and Processes::Metabolic Phenomena::Metabolism::Hydroxylation
KW  - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Molecular Mechanisms of Pharmacological Action::Enzyme Inhibitors::Protease Inhibitors::Proteasome Inhibitors
TI  - Stemness of Human Pluripotent Cells: Hypoxia-Like Response Induced by Low Nitric Oxide
TY  - research article
ER  -