TY - JOUR AU - Mateo, Joaquin AU - Boysen, Gunther AU - Barbieri, Christopher E AU - Bryant, Helen E AU - Castro, Elena AU - Nelson, Pete S AU - Olmos, David AU - Pritchard, Colin C AU - Rubin, Mark A AU - de-Bono, Johann S PY - 2017 DO - 10.1016/j.eururo.2016.08.037 UR - http://hdl.handle.net/10668/10413 T2 - European urology AB - For more precise, personalized care in prostate cancer (PC), a new classification based on molecular features relevant for prognostication and treatment stratification is needed. Genomic aberrations in the DNA damage repair pathway are common in PC,... LA - en PB - Elsevier KW - BRCA KW - DNA damage KW - DNA repair KW - PARP KW - Personalized medicine KW - Prostate cancer KW - Ataxia Telangiectasia Mutated Proteins KW - BRCA1 Protein KW - BRCA2 Protein KW - DNA Mismatch Repair KW - DNA Repair KW - Humans KW - Male KW - Molecular Diagnostic Techniques KW - MutL Protein Homolog 1 KW - MutS Homolog 2 Protein KW - Poly(ADP-ribose) Polymerase Inhibitors KW - Precision Medicine KW - Prognosis KW - Prostatic Neoplasms KW - Prostatic Neoplasms, Castration-Resistant KW - Recombinational DNA Repair TI - DNA Repair in Prostate Cancer: Biology and Clinical Implications. TY - research article VL - 71 ER -