RT Journal Article T1 Differential prefrontal-like deficit in children after cerebellar astrocytoma and medulloblastoma tumor A1 Vaquero, Encarna A1 Gómez, Carlos M A1 Quintero, Eliana A A1 González-Rosa, Javier J A1 Márquez, Javier K1 Adolescente K1 Animales K1 Astrocitoma K1 Enfermedades cerebelosas K1 Neoplasias cerebelosas K1 Núcleos cerebelosos K1 Cerebelo K1 Niño K1 Cognición K1 Grupos control K1 Conducta cooperativa K1 Cuervos K1 Función ejecutiva K1 Lóbulo frontal K1 Humanos K1 Meduloblastoma K1 Semántica K1 Test de Stroop K1 Pruebas de asociación de palabras AB BACKGROUNDThis study was realized thanks to the collaboration of children and adolescents who had been resected from cerebellar tumors. The medulloblastoma group (CE+, n = 7) in addition to surgery received radiation and chemotherapy. The astrocytoma group (CE, n = 13) did not receive additional treatments. Each clinical group was compared in their executive functioning with a paired control group (n = 12). The performances of the clinical groups with respect to controls were compared considering the tumor's localization (vermis or hemisphere) and the affectation (or not) of the dentate nucleus. Executive variables were correlated with the age at surgery, the time between surgery-evaluation and the resected volume.METHODSThe executive functioning was assessed by means of WCST, Complex Rey Figure, Controlled Oral Word Association Test (letter and animal categories), Digits span (WISC-R verbal scale) and Stroop test. These tests are very sensitive to dorsolateral PFC and/or to medial frontal cortex functions. The scores for the non-verbal Raven IQ were also obtained. Direct scores were corrected by age and transformed in standard scores using normative data. The neuropsychological evaluation was made at 3.25 (SD = 2.74) years from surgery in CE group and at 6.47 (SD = 2.77) in CE+ group.RESULTSThe Medulloblastoma group showed severe executive deficit (