TY - JOUR AU - Kreuz, W AU - Escuriola Ettingshausen, C AU - Vdovin, V AU - Zozulya, N AU - Plyushch, O AU - Svirin, P AU - Andreeva, T AU - Bubanská, E AU - Campos, M AU - Benedik-Dolničar, M AU - Jiménez-Yuste, V AU - Kitanovski, L AU - Klukowska, A AU - Momot, A AU - Osmulskaya, N AU - Prieto, M AU - Šalek, S Z AU - Velasco, F AU - Pavlova, A AU - Oldenburg, J AU - Knaub, S AU - Jansen, M AU - Belyanskaya, L AU - Walter, O AU - ObsITI study group AU - ObsITI committee PY - 2015 DO - 10.1111/hae.12774 UR - http://hdl.handle.net/10668/10016 T2 - Haemophilia : the official journal of the World Federation of Hemophilia AB - Development of neutralizing inhibitors against factor VIII (FVIII) is a major complication of haemophilia A treatment. The ongoing, international, open-label, uncontrolled, observational immune tolerance induction (ObsITI) study evaluates ITI, the... LA - en KW - Bonn protocol KW - factor VIII inhibitors KW - factor VIII/von Willebrand factor concentrate KW - haemophilia A KW - immune tolerance induction KW - poor prognosis for immune tolerance induction KW - Adolescent KW - Adult KW - Antibodies, Neutralizing KW - Child KW - Child, Preschool KW - Drug Combinations KW - Factor VIII KW - Female KW - Hemophilia A KW - Hemorrhage KW - Humans KW - Immune Tolerance KW - Infant KW - Male KW - Prognosis KW - Prospective Studies KW - Risk Factors KW - Safety KW - Young Adult KW - von Willebrand Factor TI - First prospective report on immune tolerance in poor risk haemophilia A inhibitor patients with a single factor VIII/von Willebrand factor concentrate in an observational immune tolerance induction study. TY - research article VL - 22 ER -