TY - JOUR AU - Cortés-Montero, Elsa AU - Rodríguez-Muñoz, María AU - Ruiz-Cantero, María Del Carmen AU - Cobos, Enrique José AU - Sánchez-Blázquez, Pilar AU - Garzón-Niño, Javier PY - 2020 DO - 10.3390/ijms22010229 SN - 1661-6596 UR - http://hdl.handle.net/10668/4108 T2 - International Journal of Molecular Sciences AB - Transient receptor potential ankyrin member 1 (TRPA1) belongs to the family of thermo TRP cation channels that detect harmful temperatures, acids and numerous chemical pollutants. TRPA1 is expressed in nervous tissue, where it participates in the... LA - en PB - MDPI KW - Transient receptor potential A1 KW - Mu opioid receptor KW - Calmodulin KW - Glutamate NMDA receptor KW - Neuropathic pain KW - Inflammatory pain KW - Hyperalgesia KW - Antinociception KW - Dorsal root ganglia KW - Spinal cord KW - Canal catiónico TRPA1 KW - Receptores opioides mu KW - Calmodulina KW - Receptores de glutamato KW - Neuralgia KW - Hiperalgesia KW - Ganglios espinales KW - Médula espinal KW - Medical Subject Headings::Organisms::Eukaryota::Animals KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Calcium-Binding Proteins::Intracellular Calcium-Sensing Proteins::Calmodulin KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathological Conditions, Anatomical::Constriction, Pathologic KW - Medical Subject Headings::Chemicals and Drugs::Organic Chemicals::Aldehydes::Formaldehyde KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Glutamates::Glutamic Acid KW - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Inflammation KW - Medical Subject Headings::Check Tags::Male KW - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Rodentia::Muridae::Murinae::Mice KW - Medical Subject Headings::Anatomy::Nervous System::Nerve Tissue KW - Medical Subject Headings::Diseases::Nervous System Diseases::Neurologic Manifestations::Pain::Neuralgia KW - Medical Subject Headings::Phenomena and Processes::Physiological Phenomena::Organ Specificity KW - Medical Subject Headings::Phenomena and Processes::Chemical Phenomena::Biochemical Phenomena::Biochemical Processes::Protein Binding KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Protein Subunits KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Carrier Proteins::Membrane Transport Proteins::Ion Channels::Ligand-Gated Ion Channels::Receptors, Ionotropic Glutamate::Receptors, N-Methyl-D-Aspartate KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Opioid KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Membrane Transport Proteins::Ion Channels::Calcium Channels::TRPP Cation Channels KW - Medical Subject Headings::Diseases::Nervous System Diseases::Neurologic Manifestations::Sensation Disorders::Somatosensory Disorders::Hyperalgesia KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Opioid::Receptors, sigma KW - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Pain Perception::Nociception KW - Medical Subject Headings::Psychiatry and Psychology::Psychological Phenomena and Processes::Mental Processes::Perception::Pain Perception::Nociception KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Blood Proteins::Ankyrins KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Cyclic::Histidine KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Proteins::Membrane Proteins::Receptors, Cell Surface::Receptors, G-Protein-Coupled::Receptors, Opioid::Receptors, Opioid, delta KW - Medical Subject Headings::Diseases::Nervous System Diseases::Neurologic Manifestations::Pain::Chronic Pain KW - Medical Subject Headings::Anatomy::Nervous System::Ganglia::Ganglia, Sensory::Ganglia, Spinal KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Spinal Cord KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Pharmacologic Actions::Therapeutic Uses::Central Nervous System Agents::Analgesics KW - Medical Subject Headings::Chemicals and Drugs::Nucleic Acids, Nucleotides, and Nucleosides::Nucleotides KW - Medical Subject Headings::Chemicals and Drugs::Amino Acids, Peptides, and Proteins::Amino Acids::Amino Acids, Acidic::Glutamates KW - Medical Subject Headings::Chemicals and Drugs::Chemical Actions and Uses::Toxic Actions::Environmental Pollutants KW - Medical Subject Headings::Anatomy::Nervous System::Central Nervous System::Brain TI - Calmodulin Supports TRPA1 Channel Association with Opioid Receptors and Glutamate NMDA Receptors in the Nervous Tissue TY - research article ER -