TY  - JOUR
AU  - Boyero, Laura
AU  - Sánchez-Gastaldo, Amparo
AU  - Alonso, Miriam
AU  - Noguera-Uclés, José Francisco
AU  - Molina-Pinelo, Sonia
AU  - Bernabé-Caro, Reyes
PY  - 2020
DO  - 10.3390/cancers12123729
UR  - http://hdl.handle.net/10668/3672
T2  - Cancers
AB  - After several decades without maintained responses or long-term survival of patients with lung cancer, novel therapies have emerged as a hopeful milestone in this research field. The appearance of immunotherapy, especially immune checkpoint...
LA  - en
PB  - MDPI
KW  - Lung cancer
KW  - Immunotherapy
KW  - Resistance mechanisms
KW  - PD-1/PD-L1
KW  - Immune checkpoint inhibitors
KW  - Monoclonal antibodies
KW  - NSCLC
KW  - SCLC
KW  - Neoplasias pulmonares
KW  - Inmunoterapia
KW  - Receptor de muerte celular programada 1
KW  - Antígeno B7-H1
KW  - Inhibidores de puntos de control inmunológico
KW  - Anticuerpos monoclonales
KW  - Carcinoma de pulmón de células no pequeñas
KW  - Carcinoma pulmonar de células pequeñas
KW  - Medical Subject Headings::Organisms::Eukaryota::Animals::Chordata::Vertebrates::Mammals::Primates::Haplorhini::Catarrhini::Hominidae::Humans
KW  - Medical Subject Headings::Anthropology, Education, Sociology and Social Phenomena::Social Sciences::Quality of Life
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cellular Microenvironment::Tumor Microenvironment
KW  - Medical Subject Headings::Analytical, Diagnostic and Therapeutic Techniques and Equipment::Therapeutics::Biological Therapy::Immunomodulation::Immunotherapy
KW  - Medical Subject Headings::Diseases::Neoplasms::Neoplasms by Site::Thoracic Neoplasms::Respiratory Tract Neoplasms::Lung Neoplasms
KW  - Medical Subject Headings::Anatomy::Hemic and Immune Systems::Immune System::Leukocytes::Leukocytes, Mononuclear::Lymphocytes::T-Lymphocytes
KW  - Medical Subject Headings::Phenomena and Processes::Cell Physiological Phenomena::Cell Physiological Processes::Signal Transduction
KW  - Medical Subject Headings::Phenomena and Processes::Microbiological Phenomena::Microbiota
KW  - Medical Subject Headings::Phenomena and Processes::Genetic Phenomena::Genetic Processes::Gene Expression Regulation::Epigenesis, Genetic
KW  - Medical Subject Headings::Diseases::Pathological Conditions, Signs and Symptoms::Pathologic Processes::Disease Attributes::Recurrence
TI  - Primary and Acquired Resistance to Immunotherapy in Lung Cancer: Unveiling the Mechanisms Underlying of Immune Checkpoint Blockade Therapy
TY  - review article
ER  -