RT Journal Article T1 Epidemiology of non-steroidal anti-inflammatory drugs consumption in Spain. The MCC-Spain study. A1 Gómez-Acebo, Inés A1 Dierssen-Sotos, Trinidad A1 de Pedro, María A1 Pérez-Gómez, Beatriz A1 Castaño-Vinyals, Gemma A1 Fernández-Villa, Tania A1 Palazuelos-Calderón, Camilo A1 Amiano, Pilar A1 Etxeberria, Jaione A1 Benavente, Yolanda A1 Fernández-Tardón, Guillermo A1 Salcedo-Bellido, Inmaculada A1 Capelo, Rocío A1 Peiró, Rosana A1 Marcos-Gragera, Rafael A1 Huerta, José M A1 Tardón, Adonina A1 Barricarte, Aurelio A1 Altzibar, Jone-Miren A1 Alonso-Molero, Jessica A1 Dávila-Batista, Verónica A1 Aragonés, Nuria A1 Pollán, Marina A1 Kogevinas, Manolis A1 Llorca, Javier K1 Aspirin K1 Cardiovascular risk K1 Gastrointestinal bleeding K1 Non-steroidal anti-inflammatory drugs K1 Propionates AB Non-steroidal anti-inflammatory drugs (NSAIDs) are widely used despite their risk of gastrointestinal bleeding or cardiovascular events. We report the profile of people taking NSAIDs in Spain, and we include demographic factors, health-related behaviours and cardiovascular disease history. Four thousand sixtyparticipants were selected using a pseudorandom number list from Family Practice lists in 12 Spanish provinces. They completed a face-to-face computerized interview on their NSAID consumption, demographic characteristics, body mass index, alcohol and tobacco consumption and medical history. In addition, participants completed a self-administered food-frequency and alcohol consumption questionnaire. Factors associated with ever and current NSAID consumption were identified by logistic regression. Women consumed more non-aspirin NSAIDs (38.8% [36.7-41.0]) than men (22.3 [20.5-24.2]), but men consumed more aspirin (11.7% [10.3-13.2]) than women (5.2% [4.3-6.3]). Consumption of non-aspirin NSAIDs decrease with age from 44.2% (39.4-49.1) in younger than 45 to 21.1% (18.3-24.2) in older than 75, but the age-pattern for aspirin usage was the opposite. Aspirin was reported by about 11% patients, as being twice as used in men (11.7%) than in women (5.2%); its consumption increased with age from 1.7% ( Non-aspirin NSAIDs were more consumed by women and aspirin by men. The age patterns of aspirin and non-aspirin NSAIDs were opposite: the higher the age, the lower the non-aspirin NSAIDs usage and the higher the aspirin consumption. People with cardiovascular risk factors or diseases consumed more aspirin, but they did not decrease their non-aspirin NSAIDs usage. YR 2018 FD 2018-09-21 LK http://hdl.handle.net/10668/12978 UL http://hdl.handle.net/10668/12978 LA en DS RISalud RD Apr 8, 2025